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Journal Articles

Unsupervised Denoising and Super-Resolution of Vascular Flow Data by Physics-Informed Machine Learning

Théophile Sautory, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2024, 146(9): 091006.
Paper No: BIO-23-1404
https://doi.org/10.1115/1.4065165
Published Online: April 17, 2024
View Articletitled, Unsupervised Denoising and Super-Resolution of Vascular Flow Data by Physics-Informed Machine Learning
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Topics: Flow (Dynamics), Resolution (Optics), Pressure, Geometry, Physics, Noise (Sound), Machine learning
Journal Articles

Automating Model Generation for Image-Based Cardiac Flow Simulation

Fanwei Kong, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2020, 142(11): 111011.
Paper No: BIO-20-1172
https://doi.org/10.1115/1.4048032
Published Online: September 11, 2020
View Articletitled, Automating Model Generation for Image-Based Cardiac Flow Simulation
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Topics: Computational fluid dynamics, Image segmentation, Simulation, Geometry, Artificial neural networks
Journal Articles

Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool

Kimberly A. Stevens Boster, Melody Dong, Jessica M. Oakes, Chiara Bellini, Vitaliy L. Rayz, John F. LaDisa, Jr., Dave Parker, Nathan M. Wilson, Shawn C. Shadden, Alison L. Marsden, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2020, 142(11): 111008.
Paper No: BIO-20-1136
https://doi.org/10.1115/1.4047479
Published Online: September 9, 2020
View Articletitled, Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool
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Topics: Computational fluid dynamics, Computer software, Modeling, Simulation, Students, Cardiovascular system, Boundary-value problems, Diseases
Journal Articles

Construction of Analysis-Suitable Vascular Models Using Axis-Aligned Polycubes

Adam R. Updegrove, Shawn C. Shadden, Nathan M. Wilson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 060906.
Paper No: BIO-18-1142
https://doi.org/10.1115/1.4040773
Published Online: April 22, 2019
View Articletitled, Construction of Analysis-Suitable Vascular Models Using Axis-Aligned Polycubes
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Topics: Algorithms, Bifurcation, B-splines, Construction, Geometry, Modeling, Biomedical imaging, Image segmentation, Blood flow, Cardiovascular system
Journal Articles

Reduced Order Models for Transstenotic Pressure Drop in the Coronary Arteries

Mehran Mirramezani, Scott L. Diamond, Harold I. Litt, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2019, 141(3): 031005.
Paper No: BIO-18-1292
https://doi.org/10.1115/1.4042184
Published Online: January 18, 2019
View Articletitled, Reduced Order Models for Transstenotic Pressure Drop in the Coronary Arteries
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Topics: Algebra, Computational fluid dynamics, Coronary arteries, Flow (Dynamics), Modeling, Pressure, Pressure drop, Simulation, Blood flow
Journal Articles

A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package

Hongzhi Lan, Adam Updegrove, Nathan M. Wilson, Gabriel D. Maher, Shawn C. Shadden, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2018, 140(2): 024501.
Paper No: BIO-17-1574
https://doi.org/10.1115/1.4038751
Published Online: January 25, 2018
View Articletitled, A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package
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Topics: Cardiovascular system, Computer software, Graphical user interfaces, Image segmentation, Modeling, Simulation, Vessels, Pipelines, Visualization, Boundary-value problems
Journal Articles

Computational Assessment of the Relation Between Embolism Source and Embolus Distribution to the Circle of Willis for Improved Understanding of Stroke Etiology

Debanjan Mukherjee, Neel D. Jani, Kartiga Selvaganesan, Christopher L. Weng, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2016, 138(8): 081008.
Paper No: BIO-16-1072
https://doi.org/10.1115/1.4033986
Published Online: July 12, 2016
View Articletitled, Computational Assessment of the Relation Between Embolism Source and Embolus Distribution to the Circle of Willis for Improved Understanding of Stroke Etiology
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Topics: Brain, Cerebral arteries, Flow (Dynamics), Hemodynamics, Particulate matter, Vessels, Aorta, Anatomy, Particle dynamics
Journal Articles

Characterizations and Correlations of Wall Shear Stress in Aneurysmal Flow

Amirhossein Arzani, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2016, 138(1): 014503.
Paper No: BIO-15-1221
https://doi.org/10.1115/1.4032056
Published Online: December 8, 2015
View Articletitled, Characterizations and Correlations of Wall Shear Stress in Aneurysmal Flow
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Topics: Flow (Dynamics), Shear stress, Computational fluid dynamics, Aneurysms, Spacetime
Journal Articles

A Coupled Lumped-Parameter and Distributed Network Model for Cerebral Pulse-Wave Hemodynamics

Jaiyoung Ryu, Xiao Hu, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2015, 137(10): 101009.
Paper No: BIO-15-1227
https://doi.org/10.1115/1.4031331
Published Online: September 3, 2015
View Articletitled, A Coupled Lumped-Parameter and Distributed Network Model for Cerebral Pulse-Wave Hemodynamics
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Topics: Blood flow, Flow (Dynamics), Pressure, Vessels, Waves, Hemodynamics, Cerebral arteries, Compression, Modeling
Includes: Supplementary data
Journal Articles

Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms

Kirk B. Hansen, Amirhossein Arzani, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2015, 137(4): 041005.
Paper No: BIO-14-1355
https://doi.org/10.1115/1.4029580
Published Online: April 1, 2015
View Articletitled, Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms
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Topics: Aneurysms, Platelets, Stress, Flow (Dynamics), Particulate matter, Physiology, Computational fluid dynamics
Proceedings Papers

Progression of Abdominal Aortic Aneurysm: Effect of Lagrangian Transport and Hemodynamic Parameters

Amirhossein Arzani, Ga Young Suh, Michael V. McConnell, Ronald L. Dalman, Shawn C. Shadden
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT01A004, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14643
https://doi.org/10.1115/SBC2013-14643
View Paper titled, Progression of Abdominal Aortic Aneurysm: Effect of Lagrangian Transport and Hemodynamic Parameters
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Topics: Aneurysms, Hemodynamics, Flow (Dynamics), Computational fluid dynamics, Aorta, Diseases, Topology, Biomechanics, Blood, Blood flow
Proceedings Papers

In Vivo Measurements of Blood Transport Patterns and Stasis in the Human Left Ventricle

Sahar Hendabadi, Javier Bermejo, Yolanda Benito, Raquel Yotti, Francisco Fernández-Avilés, Juan C. del Álamo, Shawn C. Shadden
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT13A023, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14665
https://doi.org/10.1115/SBC2013-14665
View Paper titled, In Vivo Measurements of Blood Transport Patterns and Stasis in the Human Left Ventricle
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Topics: Blood, Flow (Dynamics), Vortices, Waves, Computation, Cycles, Echocardiography, Hemodynamics, Risk, Thrombosis
Proceedings Papers

Predilections of Cardiogenic Embolic Transport to the Cerebral Versus Peripheral Arteries

Shawn C. Shadden, Ian A. Carr, Naohiko Nemoto, Robert S. Schwartz, John R. Lesser
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT13A024, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14667
https://doi.org/10.1115/SBC2013-14667
View Paper titled, Predilections of Cardiogenic Embolic Transport to the Cerebral Versus Peripheral Arteries
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Topics: Aorta, Bifurcation, Biomedical imaging, Blood flow, Brain, Cerebral arteries, Computer simulation, Flow (Dynamics), Fluid dynamics, Particulate matter
Proceedings Papers

Healthy vs Diseased Transport and Mixing in the Human Left Ventricle

Sahar Hendabadi, Juan C. del Alamo, Shawn C. Shadden
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 81-82, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80788
https://doi.org/10.1115/SBC2012-80788
View Paper titled, Healthy vs Diseased Transport and Mixing in the Human Left Ventricle
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Topics: Blood, Blood flow, Dynamics (Mechanics), Echocardiography, Flow (Dynamics), Heart failure, Magnetic resonance imaging, Ultrasound, Vorticity
Proceedings Papers

Potential Pathways for Platelet Activation

Shawn C. Shadden, Sahar Hendabadi
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 889-890, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80474
https://doi.org/10.1115/SBC2012-80474
View Paper titled, Potential Pathways for Platelet Activation
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Topics: Platelets, Flow (Dynamics), Cardiovascular system, Topology, Trajectories (Physics)
Proceedings Papers

CFD Challenge: Solutions Using a Second Order Accurate, Stabilized Finite Element Solver

Amirhossein Arzani, Nathan Wilson, Shawn C. Shadden
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 143-144, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80661
https://doi.org/10.1115/SBC2012-80661
View Paper titled, CFD Challenge: Solutions Using a Second Order Accurate, Stabilized Finite Element Solver
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Topics: Computational fluid dynamics, Finite element analysis, Cardiovascular system, Dynamic systems, Engineering simulation, Flow (Dynamics), Hemodynamics, Simulation
Proceedings Papers

Transport and Mixing in Patient Specific Abdominal Aortic Aneurysms With Lagrangian Coherent Structures

Amirhossein Arzani, Shawn C. Shadden
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 9-10, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80475
https://doi.org/10.1115/SBC2012-80475
View Paper titled, Transport and Mixing in Patient Specific Abdominal Aortic Aneurysms With Lagrangian Coherent Structures
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Topics: Aneurysms, Flow (Dynamics), Hemodynamics, Computation, Particulate matter, Rupture, Shear stress, Topology, Turbulence
Proceedings Papers

Customization of the Fontan Y-Graft: Are Unequal Branches Necessary for Optimal Hepatic Flow Distribution?

Weiguang Yang, Jeffrey A. Feinstein, Irene E. Vignon-Clementel, Shawn C. Shadden, Alison L. Marsden
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 461-462, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53752
https://doi.org/10.1115/SBC2011-53752
View Paper titled, Customization of the Fontan Y-Graft: Are Unequal Branches Necessary for Optimal Hepatic Flow Distribution?
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Topics: Diseases, Flow (Dynamics), Junctions, Liver, Pulmonary artery, Surgery
Journal Articles

Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge

David A. Steinman, Yiemeng Hoi, Paul Fahy, Liam Morris, Michael T. Walsh, Nicolas Aristokleous, Andreas S. Anayiotos, Yannis Papaharilaou, Amirhossein Arzani, Shawn C. Shadden, Philipp Berg, Gábor Janiga, Joris Bols, Patrick Segers, Neil W. Bressloff, Merih Cibis, Frank H. Gijsen, Salvatore Cito, Jordi Pallarés, Leonard D. Browne, Jennifer A. Costelloe, Adrian G. Lynch, Joris Degroote, Jan Vierendeels, Wenyu Fu, Aike Qiao, Simona Hodis, David F. Kallmes, Hardeep Kalsi, Quan Long, Vitaly O. Kheyfets, Ender A. Finol, Kenichi Kono, Adel M. Malek, Alexandra Lauric, Prahlad G. Menon, Kerem Pekkan, Mahdi Esmaily Moghadam, Alison L. Marsden, Marie Oshima, Kengo Katagiri, Véronique Peiffer, Yumnah Mohamied, Spencer J. Sherwin, Jens Schaller, Leonid Goubergrits, Gabriel Usera, Mariana Mendina, Kristian Valen-Sendstad, Damiaan F. Habets, Jianping Xiang, Hui Meng, Yue Yu, George E. Karniadakis, Nicholas Shaffer, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021016.
Paper No: BIO-12-1542
https://doi.org/10.1115/1.4023382
Published Online: February 11, 2013
View Articletitled, Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge
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Topics: Computational fluid dynamics, Flow (Dynamics), Pressure, Pressure drop, Aneurysms, Cycles
Journal Articles

Optimization of a Y-Graft Design for Improved Hepatic Flow Distribution in the Fontan Circulation

Weiguang Yang, Jeffrey A. Feinstein, Shawn C. Shadden, Irene E. Vignon-Clementel, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2013, 135(1): 011002.
Paper No: BIO-11-1531
https://doi.org/10.1115/1.4023089
Published Online: December 27, 2012
View Articletitled, Optimization of a Y-Graft Design for Improved Hepatic Flow Distribution in the Fontan Circulation
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Topics: Design, Flow (Dynamics), Liver, Optimization, Geometry