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Journal Articles

A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine

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Atheer Awad, Alvaro Goyanes, Abdul W. Basit, Ahmed S. Zidan, Changxue Xu, Wei Li, Roger J. Narayan, Roland K. Chen
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Review Articles
J. Manuf. Sci. Eng. January 2023, 145(1): 010802.
Paper No: MANU-22-1279
https://doi.org/10.1115/1.4056199
Published Online: December 1, 2022
View Articletitled, A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine
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Topics: Additive manufacturing, Biomedicine, Drugs, Manufacturing, Printing, Extruding, Drug delivery systems
Journal Articles

Photo-Responsive Hydrogel Microneedles With Interlocking Control for Easy Extraction in Sustained Ocular Drug Delivery

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Maher Amer, Xiang Ni, Ming Xian, Roland K. Chen
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. February 2022, 5(1): 011001.
Paper No: JESMDT-21-1015
https://doi.org/10.1115/1.4052627
Published Online: October 28, 2021
View Articletitled, Photo-Responsive Hydrogel Microneedles With Interlocking Control for Easy Extraction in Sustained Ocular Drug Delivery
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Topics: Adhesion, Drug delivery systems, Hydrogels, Microneedles, Manufacturing, Adhesives
Proceedings Papers

A Feasibility Study on 3D Printed Biopsy Needles: Pronged Tips and Internal Features Affect on Tissue Yield

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Anika VanDeen, Maher Amer, Luiz Longo, Chrissy Eckstrand, Tom Wilkinson, Roland K. Chen
Proc. ASME. MSEC2020, Volume 1: Additive Manufacturing; Advanced Materials Manufacturing; Biomanufacturing; Life Cycle Engineering; Manufacturing Equipment and Automation, V001T03A017, September 3, 2020
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2020-8518
https://doi.org/10.1115/MSEC2020-8518
View Paper titled, A Feasibility Study on 3D Printed Biopsy Needles: Pronged Tips and Internal Features Affect on Tissue Yield
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Topics: Additive manufacturing, Biological tissues, Needles, Accounting, Biomedicine, Cancer, Design, Diseases, Geometry, Stainless steel
Journal Articles

Hydrogel-Forming Microneedle Arrays for Sustained and Controlled Ocular Drug Delivery

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Maher Amer, Roland K. Chen
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. November 2020, 3(4): 041003.
Paper No: JESMDT-20-1022
https://doi.org/10.1115/1.4048481
Published Online: October 13, 2020
View Articletitled, Hydrogel-Forming Microneedle Arrays for Sustained and Controlled Ocular Drug Delivery
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Topics: Drug delivery systems, Drugs, Hydrogels, Microneedles, Design
Journal Articles

Dynamic Impedance Monitoring for Large Diameter Vessel Sealing Using Bipolar Electrosurgery

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Xiaoran Li, Wei Li, Che-Hao Yang, Roland K. Chen
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research-Article
J. Med. Devices. June 2020, 14(2): 021006.
Paper No: MED-19-1188
https://doi.org/10.1115/1.4046653
Published Online: April 10, 2020
View Articletitled, Dynamic Impedance Monitoring for Large Diameter Vessel Sealing Using Bipolar Electrosurgery
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Topics: Heating, Sealing (Process), Vessels, Finite element analysis, Pressure, Blood, Blood vessels
Proceedings Papers

A New Concept of Electrosurgical Tissue Joining Process Using Sequential Compression for Minimal Thermal Damage

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Che-Hao Yang, Maher Amer, Wei Li, Roland K. Chen
Proc. ASME. MSEC2019, Volume 1: Additive Manufacturing; Manufacturing Equipment and Systems; Bio and Sustainable Manufacturing, V001T05A007, June 10–14, 2019
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2019-2946
https://doi.org/10.1115/MSEC2019-2946
View Paper titled, A New Concept of Electrosurgical Tissue Joining Process Using Sequential Compression for Minimal Thermal Damage
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Topics: Biological tissues, Compression, Damage, Joining, Surgery, Electrodes, Energy consumption, Finite element model, Temperature, Tensile strength
Proceedings Papers

Dynamic Impedance Monitoring of Large Diameter-Vessel Sealing in Bipolar Electrosurgeries

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Xiaoran Li, Che-Hao Yang, Roland K. Chen, Wei Li
Proc. ASME. MSEC2019, Volume 1: Additive Manufacturing; Manufacturing Equipment and Systems; Bio and Sustainable Manufacturing, V001T05A011, June 10–14, 2019
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2019-3033
https://doi.org/10.1115/MSEC2019-3033
View Paper titled, Dynamic Impedance Monitoring of Large Diameter-Vessel Sealing in Bipolar Electrosurgeries
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Topics: Sealing (Process), Vessels, Biological tissues, Blood vessels, Pressure, Surgery, Blood, Blood flow, Carotid arteries, Finite element analysis
Journal Articles

Characterization of the Electrosurgical Tissue Joining Process Using Dynamic Impedance and Energy Efficiency

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Che-Hao Yang, Wei Li, Roland K. Chen
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Research-Article
J. Manuf. Sci. Eng. May 2019, 141(5): 054502.
Paper No: MANU-18-1865
https://doi.org/10.1115/1.4043267
Published Online: April 2, 2019
View Articletitled, Characterization of the Electrosurgical Tissue Joining Process Using Dynamic Impedance and Energy Efficiency
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Topics: Biological tissues, Compression, Joining, Tensile strength, Energy efficiency
Proceedings Papers

Effects of Compression Force and Heating Power on Bipolar Tissue Welding

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Xiaoran Li, Roland K. Chen, Wei Li
Proc. ASME. MSEC2018, Volume 1: Additive Manufacturing; Bio and Sustainable Manufacturing, V001T05A011, June 18–22, 2018
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2018-6702
https://doi.org/10.1115/MSEC2018-6702
View Paper titled, Effects of Compression Force and Heating Power on Bipolar Tissue Welding
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Topics: Biological tissues, Compression, Heating, Welding, Surgery, Damage, Failure
Proceedings Papers

Experimental Study on the Electrosurgical Tissue Joining Process With Process Parameter Monitoring for Quality Control

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Che-Hao Yang, Roland K. Chen, Scott Phillips, Josh Ramsay, Wei Li
Proc. ASME. MSEC2018, Volume 1: Additive Manufacturing; Bio and Sustainable Manufacturing, V001T05A008, June 18–22, 2018
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2018-6637
https://doi.org/10.1115/MSEC2018-6637
View Paper titled, Experimental Study on the Electrosurgical Tissue Joining Process With Process Parameter Monitoring for Quality Control
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Topics: Biological tissues, Joining, Quality control, Compression, Damage, Energy consumption, Surgery, Temperature, Tensile strength
Proceedings Papers

Measurement of Tissue Thermal Conductivity With Variable Thermal Dose During an Electrosurgical Joining Process

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Che-Hao Yang, Samantha Kaonis, Roland K. Chen, Wei Li
Proc. ASME. MSEC2017, Volume 4: Bio and Sustainable Manufacturing, V004T05A005, June 4–8, 2017
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2017-2944
https://doi.org/10.1115/MSEC2017-2944
View Paper titled, Measurement of Tissue Thermal Conductivity With Variable Thermal Dose During an Electrosurgical Joining Process
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Proceedings Papers

Characterization of Tissue Thermal Conductivity During a Tissue Joining Process

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Che-Hao Yang, Yang Liu, Wei Li, Roland K. Chen
Proc. ASME. IMECE2016, Volume 3: Biomedical and Biotechnology Engineering, V003T04A076, November 11–17, 2016
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2016-66932
https://doi.org/10.1115/IMECE2016-66932
View Paper titled, Characterization of Tissue Thermal Conductivity During a Tissue Joining Process
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Topics: Biological tissues, Joining, Thermal conductivity, Damage, Heat transfer, Heat, Heating, Sealing (Process), Surgery, Temperature gradient
Journal Articles

The Effect of Compression Force Uniformity on Bipolar Tissue Welding

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Xiaoran Li, Russel Borduin, Roland K. Chen, Wei Li
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Technical Briefs
J. Manuf. Sci. Eng. May 2017, 139(5): 054501.
Paper No: MANU-16-1483
https://doi.org/10.1115/1.4035492
Published Online: January 30, 2017
View Articletitled, The Effect of Compression Force Uniformity on Bipolar Tissue Welding
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Topics: Biological tissues, Compression, Welding
Journal Articles

Measurement and Modeling of Tissue Thermal Conductivity With Variable Water Content and Compression

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Matthew W. Chastagner, Robert E. Dodde, Albert J. Shih, Wei Li, Roland K. Chen
Journal: ASME Journal of Heat and Mass Transfer
Publisher: ASME
Article Type: Technical Briefs
J. Heat Mass Transfer. July 2016, 138(7): 074503.
Paper No: HT-14-1631
https://doi.org/10.1115/1.4033078
Published Online: April 19, 2016
View Articletitled, Measurement and Modeling of Tissue Thermal Conductivity With Variable Water Content and Compression
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Topics: Biological tissues, Compression, Thermal conductivity, Water
Proceedings Papers

Nano-CT Characterization of Structural Voids and Air Bubbles in Fused Deposition Modeling for Additive Manufacturing

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Roland K. Chen, Terris T. Lo, Lei Chen, Albert J. Shih
Proc. ASME. MSEC2015, Volume 1: Processing, V001T02A071, June 8–12, 2015
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2015-9462
https://doi.org/10.1115/MSEC2015-9462
View Paper titled, Nano-CT Characterization of Structural Voids and Air Bubbles in Fused Deposition Modeling for Additive Manufacturing
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Topics: Additive manufacturing, Bubbles, Modeling, Fibers, Materials testing, Bonding, Computerized tomography, Experimental design, Geometry, Necking
Journal Articles

Study of Insertion Force and Deformation for Suturing With Precurved NiTi Guidewire

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Yancheng Wang, Roland K. Chen, Bruce L. Tai, Kai Xu, Albert J. Shih
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2015, 137(4): 041004.
Paper No: BIO-14-1318
https://doi.org/10.1115/1.4029311
Published Online: April 1, 2015
View Articletitled, Study of Insertion Force and Deformation for Suturing With Precurved NiTi Guidewire
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Topics: Deformation, Needles, Nickel titanium alloys, Shapes, Wire, Magnetic sensors, Endoscopic devices, Manufacturing
Proceedings Papers

Advanced Five-Plane Lancet Needle Design, Grinding, and Tissue Insertion

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Yancheng Wang, Roland K. Chen, Bruce L. Tai, Albert J. Shih
Proc. ASME. MSEC2014, Volume 2: Processing, V002T02A028, June 9–13, 2014
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2014-4046
https://doi.org/10.1115/MSEC2014-4046
View Paper titled, Advanced Five-Plane Lancet Needle Design, Grinding, and Tissue Insertion
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Topics: Biological tissues, Design, Grinding, Needles, Natural language processing, Nonlinear programming, Soft tissues, Cutting, Engineering prototypes, Geometry
Journal Articles

Bipolar Electrosurgical Vessel-Sealing Device With Compressive Force Monitoring

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Roland K. Chen, Matthew W. Chastagner, James D. Geiger, Albert J. Shih
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2014, 136(6): 061001.
Paper No: BIO-13-1370
https://doi.org/10.1115/1.4027269
Published Online: April 18, 2014
View Articletitled, Bipolar Electrosurgical Vessel-Sealing Device With Compressive Force Monitoring
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Topics: Pressure, Sealing (Process), Vessels
Journal Articles

The Needle With Lancet Point: Geometry for Needle Tip Grinding and Tissue Insertion Force

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Yancheng Wang, Bruce L. Tai, Roland K. Chen, Albert J. Shih
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Research-Article
J. Manuf. Sci. Eng. August 2013, 135(4): 041010.
Paper No: MANU-12-1169
https://doi.org/10.1115/1.4023718
Published Online: May 24, 2013
View Articletitled, The Needle With Lancet Point: Geometry for Needle Tip Grinding and Tissue Insertion Force
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Topics: Grinding, Natural language processing, Needles, Nonlinear programming, Biological tissues