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Richard L. Leask
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Proceedings Papers

Biaxial Testing of Human Pericardium: A Comparative Study of Fixed and Fresh Tissue

Tiffany C. Zigras, Naoko Nagano, Dominique Tremblay, Leonie Rouleau, Rosaire Mongrain, Raymond Cartier, Richard L. Leask
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 199-200, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176424
https://doi.org/10.1115/SBC2007-176424
View Paper titled, Biaxial Testing of Human Pericardium: A Comparative Study of Fixed and Fresh Tissue
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Topics: Biological tissues, Testing, Biomechanics, Cardiovascular system, Surgery
Proceedings Papers

Platelet and Shear Stress Interactions Within Asymmetric Stenotic Arteries

Jeff Shrum, Yahye Merhi, Richard L. Leask
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 203-204, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176446
https://doi.org/10.1115/SBC2007-176446
View Paper titled, Platelet and Shear Stress Interactions Within Asymmetric Stenotic Arteries
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Topics: Platelets, Shear stress, Adhesion, Blood, Physiology, Plasmas (Ionized gases), Shapes, Thrombosis, Vessels, Wounds
Proceedings Papers

Anatomically Correct Right Coronary Artery Model

Helen Lentzakis, Monica Farcas, Leonie Rouleau, Richard L. Leask
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 791-792, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-172212
https://doi.org/10.1115/SBC2007-172212
View Paper titled, Anatomically Correct Right Coronary Artery Model
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Topics: Coronary arteries, Endothelial cells, Flow (Dynamics), Atherosclerosis, Bifurcation, Blood flow, Fluids, Geometry, Physiology, Shear stress
Proceedings Papers

Multiphoton Microscopy of Healthy and Aneurismal Human Ascending Aorta

Stacey L. Meadley, Umakanta Tripathy, Paul W. Wiseman, Richard L. Leask
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 803-804, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206152
https://doi.org/10.1115/SBC2009-206152
View Paper titled, Multiphoton Microscopy of Healthy and Aneurismal Human Ascending Aorta
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Topics: Aorta, Microscopy, Aneurysms, Blood flow, Proteins, Biological tissues, Blood, Diseases, Fibers, Mechanical properties
Proceedings Papers

Fluid Shear Stress Reduces Simvastatin Induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells

Joanna Rossi, Léonie Rouleau, Jean-Claude Tardif, Richard L. Leask
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1081-1082, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206539
https://doi.org/10.1115/SBC2009-206539
View Paper titled, Fluid Shear Stress Reduces Simvastatin Induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells
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Topics: Adhesion, Endothelial cells, Fluids, Shear stress, Blood flow, Fluid dynamics, Proteins, Tumors
Proceedings Papers

Inflammatory Response of Endothelial Cells to Wall Shear Stress in Three Dimensional Stenotic Models

Leonie Rouleau, Joanna Rossi, Jean-Claude Tardif, Rosaire Mongrain, Richard L. Leask
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 99-100, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206669
https://doi.org/10.1115/SBC2009-206669
View Paper titled, Inflammatory Response of Endothelial Cells to Wall Shear Stress in Three Dimensional Stenotic Models
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Topics: Endothelial cells, Shear stress, Physiology, Atherosclerosis, Coronary arteries, Diseases, Flow (Dynamics), Hemodynamics, Microscopy, Shapes
Proceedings Papers

Effect of Statins and Wall Shear Stress on Endothelial Cells: Morphology and F-Actin Cytoskeleton Arrangement

Melissa Dick, Richard L. Leask
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 843-844, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80585
https://doi.org/10.1115/SBC2012-80585
View Paper titled, Effect of Statins and Wall Shear Stress on Endothelial Cells: Morphology and F-Actin Cytoskeleton Arrangement
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Topics: Endothelial cells, Shear stress, Drugs
Journal Articles

Endothelial Cell Morphologic Response to Asymmetric Stenosis Hemodynamics: Effects of Spatial Wall Shear Stress Gradients

Leonie Rouleau, Monica Farcas, Jean-Claude Tardif, Rosaire Mongrain, Richard L. Leask
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. August 2010, 132(8): 081013.
https://doi.org/10.1115/1.4001891
Published Online: July 29, 2010
View Article titled, Endothelial Cell Morphologic Response to Asymmetric Stenosis Hemodynamics: Effects of Spatial Wall Shear Stress Gradients
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Topics: Endothelial cells, Flow (Dynamics), Hemodynamics, Shapes, Shear stress
Journal Articles

The Response of Human Aortic Endothelial Cells in a Stenotic Hemodynamic Environment: Effect of Duration, Magnitude, and Spatial Gradients in Wall Shear Stress

Leonie Rouleau, Joanna Rossi, Richard L. Leask
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2010, 132(7): 071015.
https://doi.org/10.1115/1.4001217
Published Online: June 4, 2010
View Article titled, The Response of Human Aortic Endothelial Cells in a Stenotic Hemodynamic Environment: Effect of Duration, Magnitude, and Spatial Gradients in Wall Shear Stress
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Topics: Adhesion, Endothelial cells, Flow (Dynamics), Hemodynamics, Proteins, Shear stress, Microscopy
Journal Articles

Effects of Diffusion Coefficients and Struts Apposition Using Numerical Simulations for Drug Eluting Coronary Stents

Rosaire Mongrain, Isam Faik, Richard L. Leask, Josep Rodés-Cabau, Éric Larose, Olivier F. Bertrand
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2007, 129(5): 733–742.
https://doi.org/10.1115/1.2768381
Published Online: February 22, 2007
View Article titled, Effects of Diffusion Coefficients and Struts Apposition Using Numerical Simulations for Drug Eluting Coronary Stents
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Topics: Blood, Coatings, Diffusion (Physics), Drugs, Polymers, Stents, Struts (Engineering), Computer simulation