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James C. Iatridis
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Proceedings Papers

Shear Mechanical Behavior of the Human Lumbar Anulus Fibrosus and the Effects of Degeneration

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James C. Iatridis, Sanjay Kumar, Leena Krishnan, Bernard A. Rawlins, Mark Weidenbaum, Van C. Mow
Proc. ASME. IMECE96, Advances in Bioengineering, 149-150, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1158
https://doi.org/10.1115/IMECE1996-1158
View Paper titled, Shear Mechanical Behavior of the Human Lumbar Anulus Fibrosus and the Effects of Degeneration
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Topics: Mechanical behavior, Shear (Mechanics), Compressive stress, Disks, Failure, Intervertebral discs, Mechanical properties, Structural mechanics
Journal Articles

Structural and Chemical Modification to Improve Adhesive and Material Properties of Fibrin-Genipin for Repair of Annulus Fibrosus Defects in Intervertebral Disks

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Michelle A. Cruz, Steven McAnany, Nikita Gupta, Rose G. Long, Philip Nasser, David Eglin, Andrew C. Hecht, Svenja Illien-Junger, James C. Iatridis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2017, 139(8): 084501.
Paper No: BIO-16-1241
https://doi.org/10.1115/1.4036623
Published Online: June 7, 2017
View Articletitled, Structural and Chemical Modification to Improve Adhesive and Material Properties of Fibrin-Genipin for Repair of Annulus Fibrosus Defects in Intervertebral Disks
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Topics: Adhesives, Annulus, Fibers, Intervertebral discs, Maintenance, Biomechanics, Materials properties, Density, Electron microscopy, Shear modulus
Includes: Supplementary data
Journal Articles

Design Requirements for Annulus Fibrosus Repair: Review of Forces, Displacements, and Material Properties of the Intervertebral Disk and a Summary of Candidate Hydrogels for Repair

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Rose G. Long, Olivia M. Torre, Warren W. Hom, Dylan J. Assael, James C. Iatridis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2016, 138(2): 021007.
Paper No: BIO-15-1421
https://doi.org/10.1115/1.4032353
Published Online: January 27, 2016
View Articletitled, Design Requirements for Annulus Fibrosus Repair: Review of Forces, Displacements, and Material Properties of the Intervertebral Disk and a Summary of Candidate Hydrogels for Repair
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Topics: Biological tissues, Biomaterials, Design, Hydrogels, Maintenance, Materials properties, Shear (Mechanics), Testing, Annulus, Pressure
Includes: Supplementary data
Proceedings Papers

Development of a System for Application of Dynamic Mechanical Compression on Intervertebral Discs in Organ Culture and Investigation of Load Magnitude Effects

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Casey L. Korecki, Jeffrey J. MacLean, James C. Iatridis
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 823-824, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176569
https://doi.org/10.1115/SBC2007-176569
View Paper titled, Development of a System for Application of Dynamic Mechanical Compression on Intervertebral Discs in Organ Culture and Investigation of Load Magnitude Effects
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Topics: Compression, Intervertebral discs, Stress, Annulus, Biological tissues, Biomechanics, Boundary-value problems, Disks
Proceedings Papers

Effect of Age and Frequency on Intervertebral Disc Cell Response to Dynamic Compression

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Casey L. Korecki, Catherine K. Kuo, Rocky S. Tuan, James C. Iatridis
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 825-826, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176595
https://doi.org/10.1115/SBC2007-176595
View Paper titled, Effect of Age and Frequency on Intervertebral Disc Cell Response to Dynamic Compression
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Topics: Compression, Intervertebral discs, Biological tissues, Chondrocytes, Hydrostatics, Stress, Agar, Annulus, Fibroblasts, Mechanobiology
Proceedings Papers

Asymmetric Loading Promotes Early Signs of Intervertebral Disc Degeneration in Large Animal Organ Culture

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Casey L. Korecki, Benjamin A. Walter, Karolyn E. Godburn, James C. Iatridis
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 151-152, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206491
https://doi.org/10.1115/SBC2009-206491
View Paper titled, Asymmetric Loading Promotes Early Signs of Intervertebral Disc Degeneration in Large Animal Organ Culture
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Topics: Intervertebral discs, Wounds, Boundary-value problems, Compression, Disks, Risk, Shear (Mechanics), Stress
Proceedings Papers

Measurement of Local Strains in Intervertebral Disc Anulus Fibrosus Tissue Under Dynamic Shear: Contributions of Matrix Fiber Orientation and Elastin Content

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Arthur J. Michalek, Mark R. Buckley, Lawrence J. Bonassar, Itai Cohen, James C. Iatridis
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 395-396, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204317
https://doi.org/10.1115/SBC2009-204317
View Paper titled, Measurement of Local Strains in Intervertebral Disc Anulus Fibrosus Tissue Under Dynamic Shear: Contributions of Matrix Fiber Orientation and Elastin Content
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Topics: Biological tissues, Fibers, Intervertebral discs, Shear (Mechanics), Failure, Physiology, Shear deformation
Proceedings Papers

An Analytical Model Describing Intervertebral Disc Mechanics Following a Needle Puncture Injury

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Arthur J. Michalek, James C. Iatridis
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 635-636, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206493
https://doi.org/10.1115/SBC2009-206493
View Paper titled, An Analytical Model Describing Intervertebral Disc Mechanics Following a Needle Puncture Injury
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Topics: Intervertebral discs, Needles, Wounds, Disks, Patient treatment, Railroad passenger cars, Stiffness, Stress
Proceedings Papers

Genipin-Crosslinked Fibrin Hydrogels Modified With Collagen or Fibronectin as an Annulus Fibrosus Sealant

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Clare Canal Guterl, Tyler Kim, Steven B. Nicoll, James C. Iatridis
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1151-1152, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80913
https://doi.org/10.1115/SBC2012-80913
View Paper titled, Genipin-Crosslinked Fibrin Hydrogels Modified With Collagen or Fibronectin as an Annulus Fibrosus Sealant
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Topics: Annulus, Hydrogels, Sealants, Biological tissues, Mechanical properties, Proteins, Adhesives, Cartilage, Discectomies, Food and Drug Administration
Journal Articles

Penetrating Annulus Fibrosus Injuries Affect Dynamic Compressive Behaviors of the Intervertebral Disc Via Altered Fluid Flow: An Analytical Interpretation

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Arthur J. Michalek, James C. Iatridis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2011, 133(8): 084502.
https://doi.org/10.1115/1.4004915
Published Online: September 21, 2011
View Articletitled, Penetrating Annulus Fibrosus Injuries Affect Dynamic Compressive Behaviors of the Intervertebral Disc Via Altered Fluid Flow: An Analytical Interpretation
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Topics: Annulus, Disks, Fluid dynamics, Fluids, Wounds, Intervertebral discs, Deformation, Stiffness
Journal Articles

Spatially Resolved Streaming Potentials of Human Intervertebral Disk Motion Segments Under Dynamic Axial Compression

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James C. Iatridis, Masaru Furukawa, Ian A. F. Stokes, Mack G. Gardner-Morse, Jeffrey P. Laible
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2009, 131(3): 031006.
https://doi.org/10.1115/1.3005164
Published Online: January 6, 2009
View Articletitled, Spatially Resolved Streaming Potentials of Human Intervertebral Disk Motion Segments Under Dynamic Axial Compression
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Topics: Compression, Disks, Electrodes, Intervertebral discs, Stress, Fluid dynamics, Density, Fluids, Permeability, Biological tissues
Proceedings Papers

Mechanical Damage to the Intervertebral Disc Annulus Fibrosus Subjected to Cyclic Tensile Loading

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David A. Ryan, Jeffrey J. MacLean, James C. Iatridis
Proc. ASME. IMECE2003, Advances in Bioengineering, 391-392, November 15–21, 2003
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2003-43302
https://doi.org/10.1115/IMECE2003-43302
View Paper titled, Mechanical Damage to the Intervertebral Disc Annulus Fibrosus Subjected to Cyclic Tensile Loading
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Topics: Annulus, Damage, Intervertebral discs, Biological tissues, Cycles, Deformation, Disks, Elongation, Materials properties, Stress
Proceedings Papers

Effects of Swelling Conditions on the Compressive Properties of Nucleus Pulposus From Bovine Intervertebral Discs

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David T. Korda, Delphine Perie, James C. Iatridis
Proc. ASME. IMECE2004, Advances in Bioengineering, 369-370, November 13–19, 2004
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2004-59663
https://doi.org/10.1115/IMECE2004-59663
View Paper titled, Effects of Swelling Conditions on the Compressive Properties of Nucleus Pulposus From Bovine Intervertebral Discs
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Topics: Intervertebral discs, Disks, Stress, Water, Annulus, Compression, Hydrostatic pressure, Materials properties
Proceedings Papers

Organ Culture System for Mechanobiology Studies of the Intervertebral Disc

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Cynthia R. Lee, Mauro Alini, James C. Iatridis
Proc. ASME. IMECE2004, Advances in Bioengineering, 313-314, November 13–19, 2004
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2004-61248
https://doi.org/10.1115/IMECE2004-61248
View Paper titled, Organ Culture System for Mechanobiology Studies of the Intervertebral Disc
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Topics: Intervertebral discs, Mechanobiology, Disks, Biology, Stress, Tissue engineering, Water
Journal Articles

A Removable Precision Device for In-Vivo Mechanical Compression of Rat Tail Intervertebral Discs

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Justin M. Stinnett-Donnelly, Jeffrey J. MacLean, James C. Iatridis
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research Papers
J. Med. Devices. March 2007, 1(1): 56–61.
https://doi.org/10.1115/1.2355692
Published Online: August 14, 2006
View Articletitled, A Removable Precision Device for In-Vivo Mechanical Compression of Rat Tail Intervertebral Discs
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Topics: Compression, Design, Intervertebral discs, Mechanobiology, Stress, Surgery, Disks, Pneumatic systems, Control systems
Journal Articles

Influence of Fixed Charge Density Magnitude and Distribution on the Intervertebral Disc: Applications of a Poroelastic and Chemical Electric (PEACE) Model

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James C. Iatridis, Assistant Professor, Jeffrey P. Laible, Professor, Martin H. Krag, Professor
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2003, 125(1): 12–24.
https://doi.org/10.1115/1.1537190
Published Online: February 14, 2003
View Articletitled, Influence of Fixed Charge Density Magnitude and Distribution on the Intervertebral Disc: Applications of a Poroelastic and Chemical Electric (PEACE) Model
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Topics: Density, Disks, Electric potential, Finite element analysis, Fluids, Intervertebral discs, Stress, Biological tissues, Materials properties, Water