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Proceedings Papers

Simulation of Turbulent Pulsatile Flow Past a Mechanical Heart Valve

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Danny Bluestein, Richard T. Schoephoerster
Proc. ASME. IMECE96, Advances in Bioengineering, 285-286, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1226
https://doi.org/10.1115/IMECE1996-1226
View Paper titled, Simulation of Turbulent Pulsatile Flow Past a Mechanical Heart Valve
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Topics: Heart valve prostheses, Pulsatile flow, Simulation, Turbulence, Platelets, Stress, Blood, Valves, Computer simulation, Flow (Dynamics)
Journal Articles

In Memoriam: Shmuel Einav, 1942–2022

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Danny Bluestein, C. Forbes Dewey, Jr., David Elad, Morteza (Mory) Gharib, Roger D. Kamm, Barry B. Lieber, Susan S. Margulies, Marvin J. Slepian, John Tarbell, Sheldon (Shelly) Weinbaum
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: In Memoriam
J Biomech Eng. August 2022, 144(8): 080101.
Paper No: BIO-22-1168
https://doi.org/10.1115/1.4054797
Published Online: June 23, 2022
View Articletitled, In Memoriam: Shmuel Einav, 1942–2022
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Topics: Bioengineering, Biomedical engineering, Biomedicine, Cardiovascular system, Casting, Engineering teachers, Diseases, Flow (Dynamics), Mentoring, Collaboration
Journal Articles

Visions of TAVR Future: Development and Optimization of a Second Generation Novel Polymeric TAVR

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Brandon Kovarovic, Ryan Helbock, Kyle Baylous, Oren M. Rotman, Marvin J. Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061008.
Paper No: BIO-21-1420
https://doi.org/10.1115/1.4054149
Published Online: April 6, 2022
View Articletitled, Visions of TAVR Future: Development and Optimization of a Second Generation Novel Polymeric TAVR
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Topics: Design, Optimization, Stents, Valves, Stress, Shapes, Durability, Biological tissues, Polymers
Proceedings Papers

The Effects of Implantation Techniques and Vortex Shedding on Free Emboli Formation in Mechanical Heart Valves

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Yanmei Li, Danny Bluestein
Proc. ASME. IMECE99, Advances in Bioengineering, 87-88, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0390
https://doi.org/10.1115/IMECE1999-0390
View Paper titled, The Effects of Implantation Techniques and Vortex Shedding on Free Emboli Formation in Mechanical Heart Valves
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Topics: Biomedicine, Blood flow, Flow (Dynamics), Heart valve prostheses, Jets, Numerical analysis, Orifices, Particulate matter, Platelets, Risk
Proceedings Papers

Platelet Activation in Flow Past Mechanical Heart Valves

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Danny Bluestein, Jolyon Jesty, Adam E. Saltman, Irvin B. Krukenkamp, Krishnamurthy Suresh
Proc. ASME. IMECE2001, Advances in Bioengineering, 221-222, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/BED-23110
https://doi.org/10.1115/IMECE2001/BED-23110
View Paper titled, Platelet Activation in Flow Past Mechanical Heart Valves
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Topics: Flow (Dynamics), Heart valve prostheses, Platelets, Valves, Shear stress, Turbulence, Vortices, Biomedicine, Jets, Orifices
Proceedings Papers

The Effects of Implantation Techniques on Platelet Activation in a Mechanical Heart Valve: A Numerical Study

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Yanmei Li, Danny Bluestein
Proc. ASME. IMECE2000, Advances in Bioengineering, 119-120, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2544
https://doi.org/10.1115/IMECE2000-2544
View Paper titled, The Effects of Implantation Techniques on Platelet Activation in a Mechanical Heart Valve: A Numerical Study
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Topics: Heart valve prostheses, Platelets, Valves, Wakes, Vortices, Biomedicine, Blood flow, Computer simulation, Jets, Orifices
Journal Articles

Comparative Fluid–Structure Interaction Analysis of Polymeric Transcatheter and Surgical Aortic Valves' Hemodynamics and Structural Mechanics

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Ram P. Ghosh, Gil Marom, Oren M. Rotman, Marvin J. Slepian, Saurabh Prabhakar, Marc Horner, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2018, 140(12): 121002.
Paper No: BIO-17-1507
https://doi.org/10.1115/1.4040600
Published Online: September 25, 2018
View Articletitled, Comparative Fluid–Structure Interaction Analysis of Polymeric Transcatheter and Surgical Aortic Valves' Hemodynamics and Structural Mechanics
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Topics: Flow (Dynamics), Fluid structure interaction, Valves, Hemodynamics, Surgery, Stress
Journal Articles

Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics and Molecular Dynamics

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Danny Bluestein, João S. Soares, Peng Zhang, Chao Gao, Seetha Pothapragada, Na Zhang, Marvin J. Slepian, Yuefan Deng
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Frontiers Abstracts
J. Med. Devices. December 2013, 7(4): 024502.
Paper No: MED-13-1211
https://doi.org/10.1115/1.4027347
Published Online: April 28, 2014
View Articletitled, Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics and Molecular Dynamics
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets
Proceedings Papers

Risk of Rupture in Abdominal Aortic Aneurysms and Vulnerable Plaques: A Patient Based Fluid Structure Interaction Approach

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Danny Bluestein, Yared Alemu, Michalis Xenos, Peter Rissland, Jawaad Sheriff, Luis Gruberg, Shmuel Einav, John J. Ricotta
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 891-892, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192828
https://doi.org/10.1115/SBC2008-192828
View Paper titled, Risk of Rupture in Abdominal Aortic Aneurysms and Vulnerable Plaques: A Patient Based Fluid Structure Interaction Approach
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Topics: Aneurysms, Fluid structure interaction, Risk, Rupture, Engineering simulation, Simulation, Stress, Anisotropy, Geometry, Deformation
Proceedings Papers

E-Selectin Expression on Endothelial Cells in the Presence of Platelets and Cigarette Smoke Extract

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Gaurav Girdhar, Sulan Xu, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 871-872, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192154
https://doi.org/10.1115/SBC2008-192154
View Paper titled, E-Selectin Expression on Endothelial Cells in the Presence of Platelets and Cigarette Smoke Extract
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Topics: Endothelial cells, Platelets, Smoke, Risk, Shear stress, Adhesion, Cardiovascular system, Diseases, Hemodynamics, Physiology
Proceedings Papers

Damage Accumulation Model of Prosthetic Heart Valves in Forward and Reverse Flow Phases

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Yared Alemu, Michalis Xenos, Yuefan Deng, Rui Feng, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1097-1098, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193010
https://doi.org/10.1115/SBC2008-193010
View Paper titled, Damage Accumulation Model of Prosthetic Heart Valves in Forward and Reverse Flow Phases
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Topics: Damage, Flow (Dynamics), Heart valve prostheses, Geometry, Platelets, Blood, Blood flow, Dynamics (Mechanics), Engineering simulation, Multiscale modeling
Proceedings Papers

Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study

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Jawaad Sheriff, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 825-826, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192561
https://doi.org/10.1115/SBC2008-192561
View Paper titled, Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study
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Topics: Damage, Hemodynamics, Platelets, Shear stress, Blood flow, Die cutting, Flow (Dynamics), Heart valve prostheses, Optimization, Prostheses
Proceedings Papers

Risk of Rupture in AAA and Vulnerable Plaques: Patient Based FSI Simulation

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Danny Bluestein, Yared Alemu, Peter Rissland, Mikahil Britan, Idit Avrahami, Shmuel Einav, John Ricotta
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 533-534, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176781
https://doi.org/10.1115/SBC2007-176781
View Paper titled, Risk of Rupture in AAA and Vulnerable Plaques: Patient Based FSI Simulation
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Topics: Fluid structure interaction, Risk, Rupture, Simulation, Stress, Geometry, Aneurysms, Failure, Anisotropy, Coronary arteries
Proceedings Papers

Damage Accumulation Model, FSI, and Multiscale Simulations for Studying the Thrombogenic Potential of Prosthetic Heart Valves

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Danny Bluestein, Yared Alemu, Peter Rissland, Kris Dumont, Pascal Verdonck
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 535-536, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176785
https://doi.org/10.1115/SBC2007-176785
View Paper titled, Damage Accumulation Model, FSI, and Multiscale Simulations for Studying the Thrombogenic Potential of Prosthetic Heart Valves
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Topics: Damage, Fluid structure interaction, Heart valve prostheses, Simulation, Platelets, Valves, Flow (Dynamics), Stress, Blood, Blood flow
Proceedings Papers

Progressive Increase in Platelet Activation With Smoke Exposure: Human Subject and In-Vitro Studies

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Gaurav Girdhar, Sulan Xu, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 463-464, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176018
https://doi.org/10.1115/SBC2007-176018
View Paper titled, Progressive Increase in Platelet Activation With Smoke Exposure: Human Subject and In-Vitro Studies
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Topics: Platelets, Smoke, Diseases, Cardiovascular system, Chemical vapor deposition, Damage, Physiology, Risk
Proceedings Papers

Identification of a Mathematical Model for the Prediction of Platelet Damage Accumulation in Artificial Organs: A Preliminary Study

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Matteo Nobili, Jawaad Sheriff, Umberto Morbiducci, Alberto Redaelli, Danny Bluestein
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 705-706, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176165
https://doi.org/10.1115/SBC2007-176165
View Paper titled, Identification of a Mathematical Model for the Prediction of Platelet Damage Accumulation in Artificial Organs: A Preliminary Study
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Topics: Artificial organs, Damage, Platelets, Blood, Bridges (Structures), Computer simulation, Die cutting, Flow (Dynamics), Gases, Genetic algorithms
Proceedings Papers

Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics (DPD) and Molecular Dynamics (MD)

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Danny Bluestein, João S. Soares, Peng Zhang, Chao Gao, Seetha Pothapragada, Na Zhang, Marvin J. Slepian, Yuefan Deng
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T07A005, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16176
https://doi.org/10.1115/FMD2013-16176
View Paper titled, Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics (DPD) and Molecular Dynamics (MD)
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets, Thrombosis, Blood, Blood flow, Erythrocytes, Fluids
Proceedings Papers

Design Optimization of a Novel Polymeric Prosthetic Heart Valve and a Ventricular Assist Device via Device Thrombogenicity Emulation

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Thomas E. Claiborne, Wei-Che Chiu, Marvin J. Slepian, Danny Bluestein
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T10A046, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16173
https://doi.org/10.1115/FMD2013-16173
View Paper titled, Design Optimization of a Novel Polymeric Prosthetic Heart Valve and a Ventricular Assist Device via Device Thrombogenicity Emulation
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Topics: Design, Heart valve prostheses, Optimization, Ventricular assist devices, Platelets, Artificial hearts, Blood, Computer simulation, Die cutting, Hemodynamics
Journal Articles

Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD

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Wei-Che Chiu, Gaurav Girdhar, Michalis Xenos, Yared Alemu, Jõao S. Soares, Shmuel Einav, Marvin Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021014.
Paper No: BIO-13-1418
https://doi.org/10.1115/1.4026254
Published Online: February 5, 2014
View Articletitled, Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD
Open the PDF for Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD in another window
Topics: Computer simulation, Flow (Dynamics), Impellers, Platelets, Thrombosis, Ventricular assist devices, Stress
Proceedings Papers

Comparative Studies of Axial Ventricular Assist Devices (VAD) and the Effect of Outflow Cannulation

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Wei-Che Chiu, Yared Alemu, Bryan Lynch, Shmuel Einav, Marvin Slepian, Danny Bluestein
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT46A001, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14102
https://doi.org/10.1115/SBC2013-14102
View Paper titled, Comparative Studies of Axial Ventricular Assist Devices (VAD) and the Effect of Outflow Cannulation
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Topics: Outflow, Ventricular assist devices, Heart failure, Blood flow, Bridges (Structures), Design, Flow (Dynamics), Patient treatment, Physiology, Pulsatile flow