Since pacing for bradycardia began in the 1960 s, physicians and medical device companies have focused on improving the software, hardware and longevity of implantable device, without paying substantial attention to the optimal pacing site within the right ventricle (RV). Historically, apical pacing within the RV was chosen as it was easily accessible, the lead placements were relatively stable and/or rates of dislodgement/infections were low. However, more recent studies have suggested potential deleterious effects of long-term RV apical pacing: i.e., some degree of induced heart failure with associated decreased hemodynamic [1] or ventricular function [2]. Both short-term [3] and long-term [4] studies on humans have confirmed these suggested adverse effects, more specifically including, abnormal ventricular activation times, right and left ventricular dysfunctions, which have been linked to genesis of heart failure. These observations have fuelled growing interest to perform alternate site pacing,...
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University of Minnesota;
Department of Surgery,
University of Minnesota
University of Minnesota
University of Minnesota
Department of Integrative Biology & Physiology,
University of Minnesota;
Department of Surgery,
University of Minnesota;
Department of Institute of Engineering in Medicine,
University of Minnesota
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September 2013
Technical Briefs
Conus Arteriosus as an Alternate Pacing Site
Ashish Singal,
University of Minnesota;
Department of Surgery,
University of Minnesota
Ashish Singal
Department of Biomedical Engineering
,University of Minnesota;
Department of Surgery,
University of Minnesota
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Noora Hussain,
University of Minnesota
Noora Hussain
Department of Surgery
,University of Minnesota
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Anthony J. Weinhaus,
University of Minnesota
Anthony J. Weinhaus
Integrative Biology & Physiology
,University of Minnesota
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Paul A. Iaizzo
Department of Integrative Biology & Physiology,
University of Minnesota;
Department of Surgery,
University of Minnesota;
Department of Institute of Engineering in Medicine,
University of Minnesota
Paul A. Iaizzo
Department of Biomedical Engineering
,University of Minnesota
;Department of Integrative Biology & Physiology,
University of Minnesota;
Department of Surgery,
University of Minnesota;
Department of Institute of Engineering in Medicine,
University of Minnesota
Search for other works by this author on:
Ashish Singal
Department of Biomedical Engineering
,University of Minnesota;
Department of Surgery,
University of Minnesota
Noora Hussain
Department of Surgery
,University of Minnesota
Anthony J. Weinhaus
Integrative Biology & Physiology
,University of Minnesota
Paul A. Iaizzo
Department of Biomedical Engineering
,University of Minnesota
;Department of Integrative Biology & Physiology,
University of Minnesota;
Department of Surgery,
University of Minnesota;
Department of Institute of Engineering in Medicine,
University of Minnesota
Manuscript received March 15, 2013; final manuscript received April 26, 2013; published online July 3, 2013. Assoc. Editor: Arthur G. Erdman.
J. Med. Devices. Sep 2013, 7(3): 030902 (2 pages)
Published Online: July 3, 2013
Article history
Received:
March 15, 2013
Revision Received:
April 26, 2013
Citation
Singal, A., Hussain, N., Marcaccini, R., Weinhaus, A. J., and Iaizzo, P. A. (July 3, 2013). "Conus Arteriosus as an Alternate Pacing Site." ASME. J. Med. Devices. September 2013; 7(3): 030902. https://doi.org/10.1115/1.4024493
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