... on patient specific factors such as demographics, genetics, or comorbidities. National Institutes of Health 10.13039/100000002 5R01CA290182 National Science Foundation 10.13039/100000001 2246911 cell signaling systems mechanobiology growth and remodeling multiscale modeling...

... fatigue mechanics multiscale modeling U.S. Department of Defense 10.13039/100000005 HT9425-23-1-1013 Hearing disabilities negatively impact a large amount of people worldwide [ 1 – 3 ]. One of the major causes for the acoustic injury is the mechanical damage of ear tissues at both...

... the anatomy of every patient and carrying out accurate CFD simulations rather than simplifications such as blood flow distribution based on Poiseuille's law assumed in previous studies [ 45 ]. This also justifies our choice of using a multiscale model that combines CFD in an image-segmented 3D domain...

...Abhilash Awasthi; Rajneesh Sharma; Rajesh Ghosh A multiscale model for mineralized collagen fibril (MCF) is proposed by taking into account the uncertainties associated with the geometrical properties of the mineral phase and its distribution in the organic matrix. The asymptotic homogenization...

... Inhomogeneous Microstructural Interactions in Soft Tissues Under Tensile Load ,” ASME, J. Biomech. Eng. , 135 ( 1 ), p. 011008 . 10.1115/1.4023136 [27] Hadi , M. F. , Sander , E. A. , and Barocas V. H. , 2012 , “ Multiscale Model Predicts Tissue-Level Failure From Collagen Fiber-Level...

... be a useful tool in predicting the macroscale failure conditions for soft tissues and engineered tissue analogs. In addition, the multiscale model provides a framework for the study of failure in complex fiber-based mechanical systems in general. References 1 Quinn , K. P. , and Winkelstein , B...