... received May 29, 2013; accepted manuscript posted June 17, 2013; published online September 20, 2013. Editor: Victor H. Barocas. 30 05 2012 29 05 2013 17 06 2013 The liver is one of the most frequently injured organs in abdominal trauma. Although motor vehicle collisions...

... of deformation. We demonstrate the use of this methodology by determining the minimal rheological arrangement, constitutive relationships, and model parameters for the structural response of various soft tissues, including ex vivo perfused porcine liver in indentation, ex vivo porcine brain cortical tissue...

...Andrea Bonfiglio; Kritsada Leungchavaphongse; Rodolfo Repetto; Jennifer H. Siggers In this paper, we develop a mathematical model of blood circulation in the liver lobule. We aim to find the pressure and flux distributions within a liver lobule. We also investigate the effects of changes...

...Sina Ocal; M. Umut Ozcan; Ipek Basdogan; Cagatay Basdogan The liver harvested from a donor must be preserved and transported to a suitable recipient immediately for a successful liver transplantation. In this process, the preservation period is the most critical, since it is the longest and most...

...Esra Roan In the past decade, novel tools for surgical planning and disease diagnosis have been developed to detect the liver’s mechanical properties. Some tools utilize superficial indentation type measurements to determine the elasticity of the liver parenchyma and to assume material homogeneity...

... 01 2010 18 01 2010 21 04 2010 21 04 2010 blood vessels finite element analysis liver radiation therapy tumours waveform analysis hepatocellular carcinoma radiofrequency ablation radiofrequency waveforms optimum radiofrequency waveform finite element model...

... of this study is to address the aforementioned difficulties by presenting a cost-effective SPS platform for needle insertions into the liver. The study was constrained to planar (2D) cases, but can be extended to 3D insertions. To accommodate large and velocity-dependent deformations, a hyperviscoelastic model...

...Cheng-Maw Ho; Reui-Kuo Lin; Shun-Feng Tsai; Rey-Hen Hu; Po-Chin Liang; Tony Wen-Hann Sheu; Po-Huang Lee Remnant livers will be regenerated in live donors after a large volume resection for transplantation. How the structures and hemodynamics of portal vein will evolve with liver regeneration...

..., and liver was measured before the formalin fixation and then 1 day, 4 days, and 11 days after formalin fixation. The results indicate that the formalin fixation does not cause a significant change in the tissue thermal conductivity of the tissues studied. In the clinical setting, tissues removed surgically...

... ). heat shock heat shock protein apoptosis tumor necrosis factor-α biochemistry biothermics cancer cellular biophysics liver patient treatment proteins thermal shock tumours 13 07 2008 25 02 2009 05 06 2009 2009 American Society of Mechanical Engineers ...

... isolated rat liver and exposed rat kidney tests. Perfusion in the isolated liver tests was varied by controlling the flow of the perfusate into the liver, and the perfusion in the exposed kidney tests was varied by temporarily occluding blood flow through the renal artery and vein. The perfusion estimated...

... of Hepatocytes and Nonparenchymal Cell,” FASEB J. 13, pp. 1883–1900 ) based on bFGF. 29 01 2007 22 03 2008 06 05 2008 biochemistry bioMEMS bioreactors cellular biophysics liver mass transfer microchannel flow microchannel bioreactor micropatterned coculture species...

...Prasanna Hariharan; Isaac Chang; Matthew R. Myers; Rupak K. Banerjee This study uses a reconstructed vascular geometry to evaluate the thermal response of tissue during a three-dimensional radiofrequency (rf) tumor ablation. MRI images of a sectioned liver tissue containing arterial vessels...

... the sample to the platens, which leads to a known no-slip boundary condition, but the resulting nonuniform state of stress in the sample makes it difficult to determine its material parameters. This paper presents an approach to extract the nonlinear material properties of soft tissue (such as liver...

...M. Takahashi; S. Nomura; M. Jindai; S. Shibata; X. Zhu; Y. Watanabe; K. Kawachi; N. Okabe To minimize surgical stresses including blood loss and operation time to the patients during hepatic resection, we studied the feasibility of a combination of a partial liver freezing technique and shape...

... of in vivo parallel plate electroporation of liver tissue is used to develop a better understanding of the underlying relationships between the physical parameters involved with tissue electroporation and resulting thermal damage potential. 04 04 2005 18 08 2005 biological effects of fields...

... to the permeabilization of the membrane to ions. Cryosurgery, a minimally invasive surgical procedure that uses freezing to destroy undesirable tissue, was used to investigate the hypothesis. Experimental results with liver tissue demonstrate that cell damage during freezing results in substantial changes in tissue...

..., 2001. Associate Editor: A. P. Yoganathan. 27 April 2000 25 July 2001 liver lung surgery haemodynamics The total cavo pulmonary connection (TCPC) is a common surgical correction to the congenital conditions of tricuspid atresia, univentricular heart and hypoplastic left...

...Randall E. McClelland; Robin N. Coger Establishing suitable oxygen transport pathways within bioartificial liver replacement devices continues to be an important engineering challenge. Oxygen delivery is critical since this is one of the nutrients necessary to maintain hepatocyte viability...