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Keywords: computational fluid dynamics
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Journal Articles
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2025, 147(6): 061007.
Paper No: BIO-24-1326
Published Online: May 5, 2025
.... By the application of computational fluid dynamics to model these complex physiological changes, we have not only advanced the understanding of gastric mechanics postsurgery but also highlighted the potential of computational models to inform surgical planning and improve patient outcomes. This study establishes...
Journal Articles
Hemodynamic Evaluation of Norwood Aortic Arch Geometry Compared to Native Arch Controls
Available to PurchaseAloma Blanch-Granada, John F. LaDisa, Jr., Margaret M. Samyn, Joseph R. Cava, Stephanie S. Handler, Jennifer F Gerardin, Benjamin Goot, Mehdi Maadooliat, Viktor Hraška
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2025, 147(5): 051003.
Paper No: BIO-24-1224
Published Online: March 21, 2025
... syndrome patients. We used patient-specific computational fluid dynamics (CFD) simulations incorporating physiologic boundary conditions to quantify hemodynamics for reconstructed aortic arch geometries versus native aortic arches from a control group of single ventricle patients. We hypothesized...
Topics:
Aorta,
Aortic arch,
Arches,
Blood flow,
Engineering simulation,
Geometry,
Hemodynamics,
Shear stress,
Simulation,
Computational fluid dynamics
Includes: Supplementary data
Journal Articles
Computational Fluid Dynamics Modeling of Material Transport Through Triply Periodic Minimal Surface Scaffolds for Bone Tissue Engineering
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2025, 147(3): 031007.
Paper No: BIO-24-1187
Published Online: February 4, 2025
... mechanisms and factors associated with cell-seeded, scaffold-based bone tissue engineering. The overarching goal of this study is to contribute to patient-specific, clinical treatment of bone pathology. The overall objective of the work is to establish computational fluid dynamics (CFD) models: (i...
Journal Articles
Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121002.
Paper No: BIO-24-1133
Published Online: September 6, 2024
... orientations. With our study, we have demonstrated a proof-of-concept that our computational fluid dynamics model can be applied to patient-specific geometry for pre-operative planning. Therefore, future work will focus on simulating patient-specific cases, where we assess the robustness of the valve angle...
Journal Articles
Computational Fluid Dynamics Turbulence Model and Experimental Study for a Fontan Cavopulmonary Assist Device
Available to PurchaseShreyas Sarfare, MD Shujan Ali, Alan Palazzolo, Mark Rodefeld, Tim Conover, Richard Figliola, Guruprasad Giridharan, Richard Wampler, Edward Bennett, Artem Ivashchenko
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111008.
Paper No: BIO-22-1323
Published Online: September 4, 2023
... loop and simulated with various computational fluid dynamics (CFD) models. The tests benchmarked the CFD tools for further enhancement of the CPAD design. Recommended Reynolds-Averaged Navier–Stokes (RANS) CFD approaches for the development of conventional ventricular assist devices (VAD) were found...
Journal Articles
Influence of Pulsatility and Inflow Waveforms on Tracheal Airflow Dynamics in Healthy Older Adults
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2023, 145(10): 101009.
Paper No: BIO-23-1048
Published Online: July 14, 2023
...@uabmc.edu e-mail: sbhatt@uabmc.edu 1 Corresponding author. e-mail: raghav@auburn.edu 15 02 2023 19 06 2023 14 07 2023 airflow simulations patient-specific trachea computational fluid dynamics COPD Foundation 10.13039/100008184 NCT00608764 National...
Journal Articles
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121009.
Paper No: BIO-22-1104
Published Online: October 17, 2022
.../S0962492917000046 [4]
Berg ,
P.
,
Saalfeld ,
S.
,
Voß ,
S.
,
Beuing ,
O.
, and
Janiga ,
G.
, 2019 , “
A Review on the Reliability of Hemodynamic Modeling in Intracranial Aneurysms: Why Computational Fluid Dynamics Alone Cannot Solve the Equation ,” Neurosurg. Focus ,
47...
Journal Articles
Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011013.
Paper No: BIO-21-1445
Published Online: September 19, 2022
... (CTA) images, and hemorheological parameters including time-averaged wall shear stress (TAWSS), oscillatory shear index (OSI) and relative residence time (RRT) were analyzed by computational fluid dynamics (CFD). The results showed that iliac vein stenosis could significantly increase the wall shear...
Journal Articles
Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms
Available to PurchaseChristian J. Mandrycky, Ashley N. Abel, Samuel Levy, Laurel M. Marsh, Fanette Chassagne, Venkat K. Chivukula, Sari E. Barczay, Cory M. Kelly, Louis J. Kim, Alberto Aliseda, Michael R. Levitt, Ying Zheng
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011001.
Paper No: BIO-21-1298
Published Online: August 19, 2022
... highlight the use of engineered cellularized aneurysm models for connecting computational fluid dynamics to the underlying endothelial biology that mediates disease. Fig. 2 Endothelial morphology in aneurysm regions under flow. Representative images of straight ( a ) and curved ( b ) vessel geometries...
Topics:
Aneurysms,
Computational fluid dynamics,
Endothelial cells,
Flow (Dynamics),
Hemodynamics,
Proteins,
Vessels,
Polarization (Electricity),
Polarization (Light),
Polarization (Waves)
Includes: Supplementary data
Journal Articles
Importance of Non-Newtonian Computational Fluid Modeling on Severely Calcified Aortic Valve Geometries—Insights From Quasi-Steady State Simulations
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2022, 144(11): 114501.
Paper No: BIO-21-1281
Published Online: June 16, 2022
... = computer-aided design CFD = computational fluid dynamics FEA = finite element analysis GPU = graphical processing unit OSI = oscillatory shear index Re = Reynolds number STL = stereolithography WSS = wall shear stress References [1]
Fåhræus ,
R...
Journal Articles
A Finite Element-Based Analysis of a Hemodynamics Efficient Flow Stent Suitable for Different Abdominal Aneurysm Shapes
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091006.
Paper No: BIO-21-1387
Published Online: March 30, 2022
...Ayat Nada; Mahmoud A. Fakhr; Mohamed Tarek I. El-Wakad; Mohammed A. Hassan This research aimed to examine the impact of a proposed flow stent (PFS) on different abdominal artery shapes. For that purpose, a finite element-based model using the computational fluid dynamics (CFD) method is developed...
Journal Articles
Coronary Artery Stenting Affects Wall Shear Stress Topological Skeleton
Available to PurchaseClaudio Chiastra, Valentina Mazzi, Maurizio Lodi Rizzini, Karol Calò, Anna Corti, Alessandro Acquasanta, Giuseppe De Nisco, Davide Belliggiano, Enrico Cerrato, Diego Gallo, Umberto Morbiducci
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061002.
Paper No: BIO-21-1362
Published Online: February 15, 2022
... topological skeleton. Computational fluid dynamics (CFD) simulations were performed in three stented human coronary artery geometries reconstructed from clinical images. The selected cases presented stents with different designs (i.e., two contemporary drug-eluting stents and one bioresorbable scaffold...
Topics:
Computational fluid dynamics,
Coronary arteries,
Design,
Shear stress,
Stents,
Topology,
Hemodynamics,
Flow (Dynamics),
Vessels
Includes: Supplementary data
Journal Articles
Correlation of Computational Instantaneous Wave-Free Ratio With Fractional Flow Reserve for Intermediate Multivessel Coronary Disease
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051011.
Paper No: BIO-20-1056
Published Online: March 8, 2021
... is unclear. Idealized LM coronary arteries with 34 different intermediate stenoses were created and categorized (Medina) as single and multiple lesion groups. Computational fluid dynamics modeling was performed with physiologic boundary conditions using an open-source software ( simvascular 1 ) to solve...
Journal Articles
Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I
Available to PurchaseAlaaddin Ibrahimy, Chi-Wen Christina Huang, Abraham F. Bezuidenhout, Philip A. Allen, Rafeeque A. Bhadelia, Francis Loth
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051003.
Paper No: BIO-20-1201
Published Online: March 4, 2021
... fluid (CSF) near the foramen magnum (FM). We used computational fluid dynamics (CFD) to compute patient-specific resistance to CSF motion in the spinal canal for CMI patients to determine its accuracy in predicting CAH. Fifty-one symptomatic CMI patients with cerebellar tonsillar position (CTP) ≥ 5 mm...
Journal Articles
A Hemodynamic Comparison of Myocardial Bridging and Coronary Atherosclerotic Stenosis: A Computational Model With Experimental Evaluation
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031013.
Paper No: BIO-20-1107
Published Online: January 22, 2021
... or different regarding their impacts on coronary hemodynamics. The purpose of this study was to compare the hemodynamic effects of coronary stenosis and MB using experimental and computational fluid dynamics (CFD) approaches. For CFD modeling, three MB patients with different levels of lumen obstruction, mild...
Topics:
Atherosclerosis,
Blood flow,
Computational fluid dynamics,
Computer simulation,
Flow (Dynamics),
Hemodynamics,
Pressure drop,
Simulation,
Coronary arteries,
Modeling
Includes: Supplementary data
Journal Articles
Stent-Induced Vascular Remodeling in Two-Step Stent-Assisted Coiling Treatment of Brain Aneurysms: A Closer Look Into the Hemodynamic Changes During the Stent Healing Period
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031009.
Paper No: BIO-20-1247
Published Online: December 10, 2020
... coiling (SAC). Therefore, we performed computational fluid dynamics (CFD) analysis of the blood flow in four bifurcation aneurysms focusing on the stent healing period found in SAC as a two-step maneuver. Our results show that by changing the local vasculature, the intra-aneurysmal hemodynamics changes...
Journal Articles
On the Discretization of the Power-Law Hemolysis Model
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011009.
Paper No: BIO-19-1304
Published Online: October 8, 2020
... by computational fluid dynamics (CFD) simulations has become conventional, convergence of hemolysis calculations is also essential. In this paper, convergence of the power-law hemolysis model is compared for simple flows, including pathlines with exponentially increasing and decreasing stress, in gradually...
Journal Articles
Multiscale Computational Fluid Dynamics Modeling for Personalized Liver Cancer Radioembolization Dosimetry
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011002.
Paper No: BIO-19-1356
Published Online: September 30, 2020
... and personalized dosimetry. Computational fluid dynamics (CFD) simulations were performed in a 3D hepatic arterial tree model segmented from cone-beam CT angiographic data obtained from a patient with hepatocellular carcinoma (HCC). The microsphere trajectories were predicted from the velocity field. 90 Y dose...
Includes: Supplementary data
Journal Articles
Influence of Hemodialysis Catheter Insertion on Hemodynamics in the Central Veins
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2020, 142(9): 091002.
Paper No: BIO-18-1496
Published Online: April 13, 2020
... in computational fluid dynamics (CFD) simulations of veins with CVCs. References [1]
Gunawansa ,
N.
,
Sudusinghe ,
D. H.
, and
Wijayaratne ,
D. R.
, 2018 , “
Hemodialysis Catheter-Related Central Venous Thrombosis: Clinical Approach to Evaluation and Management ,” Ann. Vasc. Surg...
Journal Articles
A Metamodeling Approach for Instant Severity Assessment and Uncertainty Quantification of Iliac Artery Stenoses
Available to PurchaseS. G. H. Heinen, K. Gashi, D. A. F van den Heuvel, J. P. P. M. de Vries, F. N. van de Vosse, T. Delhaas, W. Huberts
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2020, 142(1): 011010.
Paper No: BIO-18-1404
Published Online: October 1, 2019
... of the metamodel and in vivo measured pressure drops, the mean bias (−0.2 ± 13.7 mmHg) and the coefficient of determination (R 2 = 0.80) were as good as of the original 2D computational fluid dynamics (CFD) model. UQ results of the 2D and metamodel were comparable. Estimation of the uncertainty interval using...
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