...Umberto Morbiducci; Diego Gallo; Diana Massai; Filippo Consolo; Raffaele Ponzini; Luca Antiga; Cristina Bignardi; Marco A. Deriu; Alberto Redaelli Computational fluid dynamics (CFD) models have become very effective tools for predicting the flow field within the carotid bifurcation...

..., in particular, on the fibrous cap vulnerability. Using high-resolution magnetic resonance imaging and histology of an ex vivo human atherosclerotic carotid bifurcation, a patient-specific three-dimensional geometric model, consisting of four tissue components, is generated. The adopted constitutive model...

..., for practical purposes, be considered redundant. Image-based computational fluid dynamics simulations were carried out for N = 50 normal carotid bifurcations reconstructed from magnetic resonance imaging. Pairwise Spearman correlation analysis was performed for HWP quantifying wall shear stress magnitudes...

... of image-based CFD models of the carotid bifurcation to assumptions regarding the blood rheology. Method of Approach: CFD simulations of three different patient-specific models were carried out assuming: a reference high-shear Newtonian viscosity, two different non-Newtonian (shear-thinning) rheology...

... parameters of wall shear stress (WSS) and the oscillatory shear index (OSI) to secondary flow in the inlet velocity profiles was investigated in three realistic models of the carotid bifurcation. Method of Approach: Secondary flow profiles were generated using sufficiently long entrance lengths, to which...