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Keywords: atherosclerosis
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Journal Articles
Evaluating the Influence of Morphological Features on the Vulnerability of Lipid-Rich Plaques During Stenting
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2025, 147(2): 021007.
Paper No: BIO-24-1141
Published Online: January 3, 2025
... , N. , Sakai , R. , Yokota , Y. , ., 2022 , “ Clinical Features and Lipid Profiles of Plaque Erosion Over Lipid-Rich Plaque Versus Fibrous Plaque in Patients With Acute Coronary Syndrome ,” Atherosclerosis , 360 , pp. 47 – 52 . 10.1016/j.atherosclerosis.2022.07.008 [42] Sato...
Journal Articles
Collagen Fibril Orientation in Tissue Specimens From Atherosclerotic Plaque Explored Using Small Angle X-Ray Scattering
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2022, 144(2): 024505.
Paper No: BIO-21-1023
Published Online: December 1, 2021
....
, eds., 2004 , Atlas of Heart Disease and Stroke ,
World Health Organization ,
Geneva, Switzerland . [2]
Simionescu ,
M.
, and
Sima ,
A.
, 2012 , “
Morphology of Atherosclerotic Lesions ,” Inflammation and Atherosclerosis ,
G. Wick
and
C. Grundtman
, eds...
Journal Articles
Modeling Pulse Wave Propagation Through a Stenotic Artery With Fluid Structure Interaction: A Validation Study Using Ultrasound Pulse Wave Imaging
Available to PurchaseVittorio Gatti, Pierre Nauleau, Grigorios M. Karageorgos, Jay J. Shim, Gerard A. Ateshian, Elisa E. Konofagou
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031005.
Paper No: BIO-20-1126
Published Online: December 10, 2020
... interaction pulse wave imaging biomechanical modeling pulse wave velocity finite element modeling atherosclerosis Pulse wave imaging (PWI) is an ultrasound-based elastography method that allows indirect quantification of arterial stiffness, via estimation of pulse wave velocity (PWV) [ 1 – 4...
Journal Articles
Relation Between Neck Skin Temperature Measurement and Carotid Artery Stenosis: In-Vitro Evaluation
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2020, 142(11): 114501.
Paper No: BIO-20-1092
Published Online: October 5, 2020
...Ashish Saxena; Eddie Yin Kwee Ng; Tejas Canchi; Jun Jie Tee; Lip Koon Ng Carotid artery stenosis is a form of atherosclerosis, where thrombus formation restricts the passage of blood through the carotid artery leading to irreversible damage in the brain tissue. The presence of stenosis...
Journal Articles
Bridging Finite Element and Machine Learning Modeling: Stress Prediction of Arterial Walls in Atherosclerosis
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2019, 141(8): 084502.
Paper No: BIO-18-1518
Published Online: May 6, 2019
... finite element simulations modeling the hyperelastic behavior and resulting stress distribution. The arterial wall composition mimics vessels in atherosclerosis–a complex cardiovascular disease and one of the leading causes of death globally. We formulate the training data to predict the maximum von...
Journal Articles
Computation of Hemodynamics in Tortuous Left Coronary Artery: A Morphological Parametric Study
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2014, 136(10): 101006.
Paper No: BIO-14-1137
Published Online: August 6, 2014
.... , 1983 , “ Carotid Bifurcation Atherosclerosis. Quantitative Correlation of Plaque Localization With Flow Velocity Profiles and Wall Shear Stress ,” Circ. Res. , 53 ( 4 ), pp. 502 – 514 . 10.1161/01.RES.53.4.502 [3] Asakura , T. , and Karino , T. , 1990 , “ Flow Patterns and Spatial...
Journal Articles
The Influence of Inaccuracies in Carotid MRI Segmentation on Atherosclerotic Plaque Stress Computations
Available to PurchaseHarm A. Nieuwstadt, Lambert Speelman, Marcel Breeuwer, Aad van der Lugt, Anton F. W. van der Steen, Jolanda J. Wentzel, Frank J. H. Gijsen
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021015.
Paper No: BIO-13-1369
Published Online: February 5, 2014
... Conditions Around Neovessels in Carotid Atherosclerotic Plaque May Promote Intraplaque Hemorrhage ,” Atherosclerosis , 223 ( 2 ), pp. 321 – 326 . 10.1016/j.atherosclerosis.2012.06.015 [17] Underhill , H. R. , Hatsukami , T. S. , Fayad , A. Z. , Fuster , V. , and Yuan , C...
Journal Articles
Fatigue Crack Propagation Analysis of Plaque Rupture
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2013, 135(10): 101003.
Paper No: BIO-12-1640
Published Online: September 13, 2013
... environment, and the method proposed here may be useful for further investigation of the mechanism of plaque rupture based on in vivo patient data. plaque rupture stress intensity factor fatigue atherosclerosis Atheromatous plaque rupture can often lead to stroke or heart attack, which...
Journal Articles
A Novel Method for Quantifying Spatial Correlations Between Patterns of Atherosclerosis and Hemodynamic Factors
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021023.
Paper No: BIO-12-1463
Published Online: February 7, 2013
..., 2013; accepted manuscript posted January 18, 2013; published online February 7, 2013. Editor: Victor H. Barocas. 03 10 2012 06 01 2013 18 01 2013 Studies investigating the relation between the focal nature of atherosclerosis and hemodynamic factors are employing increasingly...
Journal Articles
Quantifying Effect of Intraplaque Hemorrhage on Critical Plaque Wall Stress in Human Atherosclerotic Plaques Using Three-Dimensional Fluid-Structure Interaction Models
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2012, 134(12): 121004.
Published Online: November 27, 2012
... to further validate our findings. intraplaque hemorrhage fluid-structure interactions magnetic resonance imaging plaque wall stress atherosclerosis vulnerability Acute cardiovascular syndromes are often associated with the rupture of atherosclerotic plaque and may occur without any warning...
Journal Articles
Three-Dimensional Geometry of the Human Carotid Artery
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. June 2012, 134(6): 064502.
Published Online: June 12, 2012
...Alexey V. Kamenskiy; Jason N. MacTaggart; Iraklis I. Pipinos; Jai Bikhchandani; Yuris A. Dzenis Accurate characterization of carotid artery geometry is vital to our understanding of the pathogenesis of atherosclerosis. Three-dimensional computer reconstructions based on medical imaging are now...
Journal Articles
Using In Vivo Cine and 3D Multi-Contrast MRI to Determine Human Atherosclerotic Carotid Artery Material Properties and Circumferential Shrinkage Rate and Their Impact on Stress/Strain Predictions
Available to PurchaseHaofei Liu, Gador Canton, Chun Yuan, Chun Yang, Kristen Billiar, Zhongzhao Teng, Allen H. Hoffman, Dalin Tang
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2012, 134(1): 011008.
Published Online: February 9, 2012
... Grant No. R01 EB004759. Consultations and guidance from Professor Roger Kamm at MIT are happily acknowledged. References 1 Underhill , H. R. , Hatsukami , T. S. , Fayad , Z. A. , Fuster , V. , and Yuan , C. , 2010 , “ MRI of Carotid Atherosclerosis: Clinical...
Journal Articles
Sequential Structural and Fluid Dynamic Numerical Simulations of a Stented Bifurcated Coronary Artery
Available to PurchaseStefano Morlacchi, Claudio Chiastra, Dario Gastaldi, Giancarlo Pennati, Gabriele Dubini, Francesco Migliavacca
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2011, 133(12): 121010.
Published Online: December 29, 2011
... by stent deployment. 23 02 2011 21 11 2011 29 12 2011 29 12 2011 bifurcation biomechanics blood vessels haemodynamics internal stresses numerical analysis physiological models stents numerical modeling atherosclerosis stenting procedures coronary bifurcations...
Journal Articles
In Vivo Serial MRI-Based Models and Statistical Methods to Quantify Sensitivity and Specificity of Mechanical Predictors for Carotid Plaque Rupture: Location and Beyond
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. June 2011, 133(6): 064503.
Published Online: June 14, 2011
... Shear Stress Region: a Case Report ,” Stroke 38 , pp. 2379 – 2381 . 10.1161/STROKEAHA.107.484766 9 Underhill , H. R. , Hatsukami , T. S. , Fayad , Z. A. , Fuster , V. , and Yuan , C. , 2010 , “ MRI of Carotid Atherosclerosis: Clinical Implications and Future...
Journal Articles
Lumen Irregularity Dominates the Relationship Between Mechanical Stress Condition, Fibrous-Cap Thickness, and Lumen Curvature in Carotid Atherosclerotic Plaque
Available to PurchaseZhongzhao Teng, Umar Sadat, Guangyu Ji, Chengcheng Zhu, Victoria E. Young, Martin J. Graves, Jonathan H. Gillard
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. March 2011, 133(3): 034501.
Published Online: February 4, 2011
... ,” J. Pathol. 0022-3417 , 181 ( 1 ), pp. 93 – 99 . 10.1002/(SICI)1096-9896(199701)181:1<93::AID-PATH696>3.0.CO;2-H Corti , R. , Hutter , R. , Badimon , J. J. , and Fuster , V. , 2004 , “ Evolving Concepts in the Triad of Atherosclerosis, Inflammation and Thrombosis...
Journal Articles
Carotid Bifurcation Hemodynamics in Older Adults: Effect of Measured Versus Assumed Flow Waveform
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2010, 132(7): 071006.
Published Online: May 26, 2010
... Research Program of the National Institute on Aging, NIH. D.A.S. also acknowledges the support of a Heart & Stroke Foundation Career Investigator Award. Ku , D. N. , Giddens , D. P. , Zarins , C. K. , and Glagov , S. , 1985 , “ Pulsatile Flow and Atherosclerosis in the Human...
Journal Articles
Effect of Geometrical Assumptions on Numerical Modeling of Coronary Blood Flow Under Normal and Disease Conditions
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2010, 132(6): 061004.
Published Online: April 21, 2010
... haemodynamics internal stresses numerical analysis physiological models coronary blood flow atherosclerosis computational fluid dynamics shear stress Coronary heart disease (CHD) is the disease that claims the most lives in the U.S., accounting for more than half of all cardiovascular deaths...
Journal Articles
3D Critical Plaque Wall Stress Is a Better Predictor of Carotid Plaque Rupture Sites Than Flow Shear Stress: An In Vivo MRI-Based 3D FSI Study
Available to PurchaseZhongzhao Teng, Gador Canton, Chun Yuan, Marina Ferguson, Chun Yang, Xueying Huang, Jie Zheng, Pamela K. Woodard, Dalin Tang
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2010, 132(3): 031007.
Published Online: February 17, 2010
... biomedical MRI diseases fracture internal stresses carotid artery atherosclerosis vulnerable plaque stroke MRI plaque rupture fluid-structure interaction Cerebrovascular events, such as stroke, are closely associated with vulnerable carotid plaques ( 1 ). In fact, more than 60% of all...
Journal Articles
Differences in Aortic Arch Geometry, Hemodynamics, and Plaque Patterns Between C57BL/6 and 129/SvEv Mice
Available to PurchaseHui Zhu, Ji Zhang, Jessica Shih, Federico Lopez-Bertoni, John R. Hagaman, Nobuyo Maeda, Morton H. Friedman
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2009, 131(12): 121005.
Published Online: November 4, 2009
... mouse model aortic arch atherosclerosis geometric risk factors stereo microscopic imaging computational fluid dynamics wall shear stress Atherosclerotic cardiovascular disease is the leading single cause of mortality worldwide ( 1 ). Over the past decade, the mouse has become an important...
Journal Articles
Vascular Cell Adhesion Molecule-1 Expression in Endothelial Cells Exposed to Physiological Coronary Wall Shear Stresses
Available to Purchase
Journal:
Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. August 2009, 131(8): 081003.
Published Online: June 19, 2009
...Lucy M. O'Keeffe; Gordon Muir; Anna V. Piterina; Tim McGloughlin Atherosclerosis is consistently found in bifurcations and curved segments of the circulatory system, indicating disturbed hemodynamics may participate in disease development. In vivo and in vitro studies have shown that endothelial...
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