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Journal Articles

Multiphysics Simulations of a Bioprinted Pulsatile Fontan Conduit

Open Access
Zinan Hu, Jessica E. Herrmann, Erica L. Schwarz, Fannie M. Gerosa, Nir Emuna, Jay D. Humphrey, Adam W. Feinberg, Tain-Yen Hsia, Mark A. Skylar-Scott, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2025, 147(7): 071001.
Paper No: BIO-24-1237
https://doi.org/10.1115/1.4068319
Published Online: May 15, 2025
View Articletitled, Multiphysics Simulations of a Bioprinted Pulsatile Fontan Conduit
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Topics: Bioprinting, Design, Electrophysiology, Fibers, Liver, Pressure, Simulation, Tension, Valves, Fluids
Journal Articles

Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves

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Kwang Bem Ko, Jung-Hee Seo, Ashish Doshi, Danielle Gottlieb Sen, Rajat Mittal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121002.
Paper No: BIO-24-1133
https://doi.org/10.1115/1.4066178
Published Online: September 6, 2024
View Articletitled, Computational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves
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Topics: Valves, Flow (Dynamics), Hemodynamics, Pulmonary artery, Pressure
Journal Articles

Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery

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Abhay B. Ramachandra, Bo Jiang, Isabella R. Jennings, Edward P. Manning, Jay D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2024, 146(8): 084501.
Paper No: BIO-23-1201
https://doi.org/10.1115/1.4064967
Published Online: March 21, 2024
View Articletitled, Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery
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Topics: Pulmonary artery, Pressure, Biomechanics, Stiffness
Includes: Supplementary data
Journal Articles

Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice

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Abhay B. Ramachandra, Nicole Mikush, Maor Sauler, Jay D. Humphrey, Edward P. Manning
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081008.
Paper No: BIO-21-1330
https://doi.org/10.1115/1.4053873
Published Online: March 11, 2022
View Articletitled, Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice
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Topics: Fibers, Lung, Pressure, Pulmonary artery, Stress, Ventilation, Energy storage, Stiffness, Diseases, Vessels
Includes: Supplementary data
Journal Articles

Morphological Analysis of the Right Ventricular Endocardial Wall in Pulmonary Hypertension

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Alifer Bordones-Crom, Sourav S. Patnaik, Prahlad G. Menon, Srinivas Murali, Ender Finol
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2021, 143(7): 074504.
Paper No: BIO-20-1292
https://doi.org/10.1115/1.4050457
Published Online: April 2, 2021
View Articletitled, Morphological Analysis of the Right Ventricular Endocardial Wall in Pulmonary Hypertension
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Topics: Shapes, Statistical analysis, Pressure, Geometry, Diseases, Cardiac cycle, Pulmonary artery, Image segmentation
Journal Articles

Computational Study of Pulmonary Flow Patterns After Repair of Transposition of Great Arteries

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Francesco Capuano, Yue-Hin Loke, Ileen Cronin, Laura J. Olivieri, Elias Balaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2019, 141(5): 051008.
Paper No: BIO-18-1414
https://doi.org/10.1115/1.4043034
Published Online: March 25, 2019
View Articletitled, Computational Study of Pulmonary Flow Patterns After Repair of Transposition of Great Arteries
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Topics: Flow (Dynamics), Pulmonary artery, Maintenance, Computational fluid dynamics
Includes: Supplementary data
Journal Articles

Experimental Study of Anisotropic Stress/Strain Relationships of Aortic and Pulmonary Artery Homografts and Synthetic Vascular Grafts

Open Access
Yueqian Jia, Yangyang Qiao, I. Ricardo Argueta-Morales, Aung Maung, Jack Norfleet, Yuanli Bai, Eduardo Divo, Alain J. Kassab, William M. DeCampli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2017, 139(10): 101003.
Paper No: BIO-16-1405
https://doi.org/10.1115/1.4037400
Published Online: August 16, 2017
View Articletitled, Experimental Study of Anisotropic Stress/Strain Relationships of Aortic and Pulmonary Artery Homografts and Synthetic Vascular Grafts
Open the PDF for Experimental Study of Anisotropic Stress/Strain Relationships of Aortic and Pulmonary Artery Homografts and Synthetic Vascular Grafts in another window
Topics: Anisotropy, Biological tissues, Mechanical properties, Pulmonary artery, Stiffness, Stress, Stress-strain relations, Vessels, Biomechanics, Aorta
Journal Articles

Biaxial Properties of the Left and Right Pulmonary Arteries in a Monocrotaline Rat Animal Model of Pulmonary Arterial Hypertension

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Erica R. Pursell, Daniela Vélez-Rendón, Daniela Valdez-Jasso
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2016, 138(11): 111004.
Paper No: BIO-16-1203
https://doi.org/10.1115/1.4034826
Published Online: October 21, 2016
View Articletitled, Biaxial Properties of the Left and Right Pulmonary Arteries in a Monocrotaline Rat Animal Model of Pulmonary Arterial Hypertension
Open the PDF for Biaxial Properties of the Left and Right Pulmonary Arteries in a Monocrotaline Rat Animal Model of Pulmonary Arterial Hypertension in another window
Topics: Diseases, Mechanical testing, Pressure, Vessels, Imaging, Pulmonary artery, Parameter estimation
Journal Articles

Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts

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Keyvan Amini Khoiy, Dipankar Biswas, Thomas N. Decker, Kourosh T. Asgarian, Francis Loth, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2016, 138(11): 111006.
Paper No: BIO-16-1216
https://doi.org/10.1115/1.4034621
Published Online: October 21, 2016
View Articletitled, Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
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Topics: Deformation, Pressure, Valves, Pulmonary artery, Annulus, Pumps, Flow (Dynamics), Errors
Includes: Supplementary data
Journal Articles

A Novel In Vivo Approach to Assess Radial and Axial Distensibility of Large and Intermediate Pulmonary Artery Branches

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A. Bellofiore, J. Henningsen, C. G. Lepak, L. Tian, A. Roldan-Alzate, H. B. Kellihan, D. W. Consigny, C. J. Francois, N. C. Chesler
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2015, 137(4): 044501.
Paper No: BIO-14-1182
https://doi.org/10.1115/1.4029578
Published Online: April 1, 2015
View Articletitled, A Novel In Vivo Approach to Assess Radial and Axial Distensibility of Large and Intermediate Pulmonary Artery Branches
Open the PDF for A Novel In Vivo Approach to Assess Radial and Axial Distensibility of Large and Intermediate Pulmonary Artery Branches in another window
Topics: Magnetic resonance imaging, Mechanical testing, Pressure, Pulmonary artery, Resolution (Optics), Imaging, Computerized tomography
Journal Articles

Insights Into Regional Adaptations in the Growing Pulmonary Artery Using a Meso-Scale Structural Model: Effects of Ascending Aorta Impingement

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Bahar Fata, Will Zhang, Rouzbeh Amini, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021009.
Paper No: BIO-13-1498
https://doi.org/10.1115/1.4026457
Published Online: February 5, 2014
View Articletitled, Insights Into Regional Adaptations in the Growing Pulmonary Artery Using a Meso-Scale Structural Model: Effects of Ascending Aorta Impingement
Open the PDF for Insights Into Regional Adaptations in the Growing Pulmonary Artery Using a Meso-Scale Structural Model: Effects of Ascending Aorta Impingement in another window
Topics: Biological tissues, Constitutive equations, Fibers, Stress, Aorta, Pulmonary artery
Journal Articles

Estimated in Vivo Postnatal Surface Growth Patterns of the Ovine Main Pulmonary Artery and Ascending Aorta

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Bahar Fata, Danielle Gottlieb, John E. Mayer, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2013, 135(7): 071010.
Paper No: BIO-12-1635
https://doi.org/10.1115/1.4024619
Published Online: June 11, 2013
View Articletitled, Estimated in Vivo Postnatal Surface Growth Patterns of the Ovine Main Pulmonary Artery and Ascending Aorta
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Topics: Aorta, Deformation, Finite element analysis, Geometry, Pulmonary artery, Shapes, Surface deformation, Biological tissues, Image segmentation, Imaging
Journal Articles

Comparison of Approaches to Quantify Arterial Damping Capacity From Pressurization Tests on Mouse Conduit Arteries

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Lian Tian, Zhijie Wang, Roderic S. Lakes, Naomi C. Chesler
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. May 2013, 135(5): 054504.
Paper No: BIO-12-1540
https://doi.org/10.1115/1.4024135
Published Online: April 24, 2013
View Articletitled, Comparison of Approaches to Quantify Arterial Damping Capacity From Pressurization Tests on Mouse Conduit Arteries
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Topics: Damping, Pressure, Stress, Pulmonary artery, Carotid arteries
Journal Articles

The Role of Collagen Synthesis in Ventricular and Vascular Adaptation to Hypoxic Pulmonary Hypertension

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David Schreier, Timothy Hacker, Gouqing Song, Naomi Chesler
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021018.
Paper No: BIO-12-1576
https://doi.org/10.1115/1.4023480
Published Online: February 7, 2013
View Articletitled, The Role of Collagen Synthesis in Ventricular and Vascular Adaptation to Hypoxic Pulmonary Hypertension
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Topics: Blood, Hemodynamics, Lung, Pressure, Ventilation, Oxygen, Pulmonary artery, Biological tissues
Journal Articles

Regional Structural and Biomechanical Alterations of the Ovine Main Pulmonary Artery During Postnatal Growth

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Bahar Fata, Christopher A. Carruthers, Gregory Gibson, Simon C. Watkins, Danielle Gottlieb, John E. Mayer, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021022.
Paper No: BIO-12-1591
https://doi.org/10.1115/1.4023389
Published Online: February 7, 2013
View Articletitled, Regional Structural and Biomechanical Alterations of the Ovine Main Pulmonary Artery During Postnatal Growth
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Topics: Biomechanics, Deformation, Fibers, Mechanical behavior, Pulmonary artery, Stress, Anisotropy, Mechanical properties, Microscopy
Journal Articles

Validation of a Pressure Diameter Method for Determining Modulus and Strain of Collagen Engagement for Long Branches of Bovine Pulmonary Arteries

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Mark Reusser, Kendall S. Hunter, Steven R. Lammers, Kurt R. Stenmark
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. May 2012, 134(5): 054501.
https://doi.org/10.1115/1.4006686
Published Online: May 25, 2012
View Articletitled, Validation of a Pressure Diameter Method for Determining Modulus and Strain of Collagen Engagement for Long Branches of Bovine Pulmonary Arteries
Open the PDF for Validation of a Pressure Diameter Method for Determining Modulus and Strain of Collagen Engagement for Long Branches of Bovine Pulmonary Arteries in another window
Topics: Biological tissues, Errors, Pressure, Pulmonary artery, Stress, Testing, Elastic moduli
Journal Articles

Obstruction-Induced Pulmonary Vascular Remodeling

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Ming-Jay Chow, Yu Zou, Huamei He, Francis X. McGowan, Jr., David Zurakowski, Yanhang Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2011, 133(11): 111009.
https://doi.org/10.1115/1.4005301
Published Online: December 8, 2011
View Articletitled, Obstruction-Induced Pulmonary Vascular Remodeling
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Topics: Assaying, Biological tissues, Echocardiography, Knee, Mechanical behavior, Mechanical properties, Physiology, Pressure, Pulmonary artery, Stress
Journal Articles

Three-Dimensional Simulations in Glenn Patients: Clinically Based Boundary Conditions, Hemodynamic Results and Sensitivity to Input Data

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G. Troianowski, C. A. Taylor, J. A. Feinstein, I. E. Vignon-Clementel
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2011, 133(11): 111006.
https://doi.org/10.1115/1.4005377
Published Online: December 1, 2011
View Articletitled, Three-Dimensional Simulations in Glenn Patients: Clinically Based Boundary Conditions, Hemodynamic Results and Sensitivity to Input Data
Open the PDF for Three-Dimensional Simulations in Glenn Patients: Clinically Based Boundary Conditions, Hemodynamic Results and Sensitivity to Input Data in another window
Topics: Boundary-value problems, Flow (Dynamics), Hemodynamics, Magnetic resonance imaging, Pressure, Shear stress, Simulation, Engineering simulation, Sensitivity analysis, Inflow
Journal Articles

A Microstructurally Driven Model for Pulmonary Artery Tissue

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Philip H. Kao, Steven R. Lammers, Lian Tian, Kendall Hunter, Kurt R. Stenmark, Robin Shandas, H. Jerry Qi
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2011, 133(5): 051002.
https://doi.org/10.1115/1.4002698
Published Online: April 8, 2011
View Articletitled, A Microstructurally Driven Model for Pulmonary Artery Tissue
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Topics: Biological tissues, Deformation, Fibers, Stress, Pulmonary artery, Modeling, Tensors
Journal Articles

Optimization of Inflow Waveform Phase-Difference for Minimized Total Cavopulmonary Power Loss

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Onur Dur, Curt G. DeGroff, Bradley B. Keller, Kerem Pekkan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2010, 132(3): 031012.
https://doi.org/10.1115/1.4000954
Published Online: February 17, 2010
View Articletitled, Optimization of Inflow Waveform Phase-Difference for Minimized Total Cavopulmonary Power Loss
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Topics: Energy dissipation, Flow (Dynamics), Hemodynamics, Inflow, Optimization, Phase shift, Physiology, Surgery, Geometry, Computational fluid dynamics