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Journal Articles

Evaluating the Combined Neurotoxicity of Amyloid Beta and Tau Oligomers in Alzheimer's Disease: A Novel Cellular-Level Criterion

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Andrey V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2025, 147(4): 041003.
Paper No: BIO-24-1287
https://doi.org/10.1115/1.4067701
Published Online: February 26, 2025
View Articletitled, Evaluating the Combined Neurotoxicity of Amyloid Beta and Tau Oligomers in Alzheimer's Disease: A Novel Cellular-Level Criterion
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Topics: Approximation, Capacitance, Diseases, Half-life, Machinery, Nucleation (Physics), Proteins, Computation
Includes: Supplementary data
Journal Articles

How Irregular Geometry and Flow Waveform Affect Pulsating Arterial Mass Transfer

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Wayne Strasser
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121011.
Paper No: BIO-23-1307
https://doi.org/10.1115/1.4065556
Published Online: October 11, 2024
View Articletitled, How Irregular Geometry and Flow Waveform Affect Pulsating Arterial Mass Transfer
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Topics: Cylinders, Flow (Dynamics), Geometry, Mass transfer, Proteins, Space, Diffusion (Physics)
Journal Articles

Simulating the Growth of TATA-Box Binding Protein-Associated Factor 15 Inclusions in Neuron Soma

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Andrey V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121010.
Paper No: BIO-24-1185
https://doi.org/10.1115/1.4066386
Published Online: October 3, 2024
View Articletitled, Simulating the Growth of TATA-Box Binding Protein-Associated Factor 15 Inclusions in Neuron Soma
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Topics: Proteins, Nucleation (Physics)
Includes: Supplementary data
Journal Articles

Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts

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Keshav A. Kailash, Jie Z. Hawes, Austin J. Cocciolone, Matthew R. Bersi, Robert P. Mecham, Jessica E. Wagenseil
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2024, 146(6): 060901.
Paper No: BIO-23-1046
https://doi.org/10.1115/1.4063272
Published Online: March 7, 2024
View Articletitled, Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts
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Topics: Anisotropy, Aorta, Biological tissues, Biomechanics, Cardiovascular system, Constitutive equations, Deformation, Fibers, Mechanical behavior, Mechanical testing
Includes: Supplementary data
Journal Articles

The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers

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Thao (Vicky) Nguyen, C. Ross Ethier
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. August 2023, 145(8): 080202.
Paper No: BIO-23-1214
https://doi.org/10.1115/1.4062744
Published Online: June 28, 2023
View Articletitled, The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers
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Topics: Deformation, Fluids, Osteoarthritis, Bioengineering, Students, Algorithms, Arches, Armor, Bearings, Biological tissues
Journal Articles

An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation

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Gozde Basara, Gokhan Bahcecioglu, Xiang Ren, Pinar Zorlutuna
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081004.
Paper No: BIO-22-1304
https://doi.org/10.1115/1.4062736
Published Online: June 21, 2023
View Articletitled, An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation
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Topics: Biological tissues, Computer simulation, Deformation, Gelatin, Proteins, Relaxation (Physics), Synchronization, Transients (Dynamics), Hydrogels
Includes: Supplementary data
Journal Articles

Dynein Dysfunction Prevents Maintenance of High Concentrations of Slow Axonal Transport Cargos at the Axon Terminal: A Computational Study

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Ivan A. Kuznetsov, Andrey V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2023, 145(7): 071001.
Paper No: BIO-22-1199
https://doi.org/10.1115/1.4056915
Published Online: March 28, 2023
View Articletitled, Dynein Dysfunction Prevents Maintenance of High Concentrations of Slow Axonal Transport Cargos at the Axon Terminal: A Computational Study
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Topics: Diffusion (Physics), Maintenance, Motors, Proteins, Engines, Boundary-value problems, Modeling
Includes: Supplementary data
Journal Articles

Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning

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Ali Behrangzade, Bruce R. Simon, William R. Wagner, Jonathan P. Vande Geest
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021002.
Paper No: BIO-22-1025
https://doi.org/10.1115/1.4055563
Published Online: October 6, 2022
View Articletitled, Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
Open the PDF for Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning in another window
Topics: Aorta, Fluids, Optimization, Permeability, Simulation, Flow (Dynamics), Thrombosis, Geometry, Finite element analysis, Platelets
Journal Articles

Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms

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Christian J. Mandrycky, Ashley N. Abel, Samuel Levy, Laurel M. Marsh, Fanette Chassagne, Venkat K. Chivukula, Sari E. Barczay, Cory M. Kelly, Louis J. Kim, Alberto Aliseda, Michael R. Levitt, Ying Zheng
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011001.
Paper No: BIO-21-1298
https://doi.org/10.1115/1.4054981
Published Online: August 19, 2022
View Articletitled, Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms
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Topics: Aneurysms, Computational fluid dynamics, Endothelial cells, Flow (Dynamics), Hemodynamics, Proteins, Vessels, Polarization (Electricity), Polarization (Light), Polarization (Waves)
Includes: Supplementary data
Journal Articles

Effect of Slp4-a on Membrane Bending During Prefusion of Vesicles in Blood-Brain Barrier

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Quyen Van Dinh, Jin Liu, Prashanta Dutta
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011006.
Paper No: BIO-22-1077
https://doi.org/10.1115/1.4054985
Published Online: August 19, 2022
View Articletitled, Effect of Slp4-a on Membrane Bending During Prefusion of Vesicles in Blood-Brain Barrier
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Topics: Brain, Ions, Membranes, Proteins, Simulation, Blood, Atoms
Includes: Supplementary data
Journal Articles

Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus

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Gabi Schwartz, Andy Morejon, Thomas M. Best, Alicia R. Jackson, Francesco Travascio
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111010.
Paper No: BIO-22-1084
https://doi.org/10.1115/1.4054931
Published Online: July 18, 2022
View Articletitled, Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus
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Topics: Anisotropy, Biological tissues, Compression, Diffusion (Physics), Fibers, Fluorescence, Proteins
Journal Articles

The Elephant in the Cell: Nuclear Mechanics and Mechanobiology

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Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. August 2022, 144(8): 080802.
Paper No: BIO-21-1401
https://doi.org/10.1115/1.4053797
Published Online: March 11, 2022
View Articletitled, The Elephant in the Cell: Nuclear Mechanics and Mechanobiology
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Topics: Biological tissues, Computer simulation, Deformation, Mechanical properties, Mechanobiology, Modeling, Proteins, Shapes, Tension, Stress
Journal Articles

Erratum: “Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia” [ASME J. Biomech. Eng., 2021, 143(3), p. 031004; DOI: 10.1115/1.4053610 ]

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Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Harifidy Randrianalisoa, Zhengpeng Qin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Errata
J Biomech Eng. August 2022, 144(8): 087001.
Paper No: BIO-21-1364
https://doi.org/10.1115/1.4053610
Published Online: February 21, 2022
View Articletitled, Erratum: “Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia” [ASME J. Biomech. Eng., 2021, 143(3), p. 031004; DOI: 10.1115/1.4053610 ]
Open the PDF for Erratum: “Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia” [ASME J. Biomech. Eng., 2021, 143(3), p. 031004; DOI: 10.1115/1.4053610 ] in another window
Topics: Proteins
Journal Articles

The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review

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Lainie E. Eisner, Ryan Rosario, Nelly Andarawis-Puri, Ellen M. Arruda
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. May 2022, 144(5): 050801.
Paper No: BIO-21-1296
https://doi.org/10.1115/1.4053086
Published Online: December 20, 2021
View Articletitled, The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review
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Topics: Biological tissues, Fibers, Mechanical behavior, Tendons, Stress, Proteins
Journal Articles

Influence of Hydroxyproline on Mechanical Behavior of Collagen Mimetic Proteins Under Fraying Deformation—Molecular Dynamics Investigations

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Atul Rawal, Kristen L. Rhinehardt, Ram V. Mohan, Max Pendse
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2021, 143(8): 081009.
Paper No: BIO-20-1494
https://doi.org/10.1115/1.4050648
Published Online: May 4, 2021
View Articletitled, Influence of Hydroxyproline on Mechanical Behavior of Collagen Mimetic Proteins Under Fraying Deformation—Molecular Dynamics Investigations
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Topics: Chain, Deformation, Proteins, Separation (Technology), Simulation, Mechanical properties, Molecular dynamics, Binding energy
Includes: Supplementary data
Journal Articles

The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction

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Mostafa Mahmoudi, Ali Farghadan, Daniel R. McConnell, Alex J. Barker, Jolanda J. Wentzel, Matthew J. Budoff, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2021, 143(4): 041002.
Paper No: BIO-20-1283
https://doi.org/10.1115/1.4049026
Published Online: December 14, 2020
View Articletitled, The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
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Topics: Atherosclerosis, Coronary arteries, Oxygen, Proteins, Shear stress, Density, Endothelial cells, Permeability, Diseases, Computational fluid dynamics
Journal Articles

Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia

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Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Randrianalisoa, Zhenpeng Qin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031004.
Paper No: BIO-20-1113
https://doi.org/10.1115/1.4049017
Published Online: December 10, 2020
View Articletitled, Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia
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Topics: Heating, Nanoparticles, Proteins, Temperature, Materials properties, Lasers, Shapes
Includes: Supplementary data
Journal Articles

Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse

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Mitchel C. Whittal, Sara Molladavoodi, Derek P. Zwambag, Magali Millecamps, Laura S. Stone, Diane E. Gregory
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2021, 143(2): 024501.
Paper No: BIO-20-1065
https://doi.org/10.1115/1.4047995
Published Online: October 8, 2020
View Articletitled, Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse
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Topics: Intervertebral discs, Lumbar spine, Stiffness, Mechanical testing, Proteins, Mechanical properties
Journal Articles

Nonlinear Elastic and Inelastic Properties of Cells

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Wonyeong Jung, Jing Li, Ovijit Chaudhuri, Taeyoon Kim
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100806.
Paper No: BIO-19-1549
https://doi.org/10.1115/1.4046863
Published Online: August 31, 2020
View Articletitled, Nonlinear Elastic and Inelastic Properties of Cells
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Topics: Atomic force microscopy, Computer simulation, Deformation, Mechanical properties, Rheology, Stress, Viscoelasticity, Relaxation (Physics), Fibroblasts, Membranes
Journal Articles

Probing Flow-Induced Biomolecular Interactions With Micro-Extensional Rheology: Tau Protein Aggregation

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H. Hosseini, A. Rangchian, M. L. Prins, C. C. Giza, J. W. Ruberti, H. P. Kavehpour
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. March 2020, 142(3): 034501.
Paper No: BIO-19-1516
https://doi.org/10.1115/1.4046330
Published Online: February 28, 2020
View Articletitled, Probing Flow-Induced Biomolecular Interactions With Micro-Extensional Rheology: Tau Protein Aggregation
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Topics: Flow (Dynamics), Proteins, Rheology, Relaxation (Physics), Shear (Mechanics)
Includes: Supplementary data