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Journal Articles

Deformation Response of the Human Lamina Cribrosa to Intracranial Pressure Lowering

Open Access
Accepted Manuscript
Kelly Clingo, Cameron A. Czerpak, Sara G. Ho, Megha Patel, Crystal Favorito, Anny Zheng, Abhay Moghekar, Harry A. Quigley, Thao (Vicky) Nguyen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng.
Paper No: BIO-24-1320
https://doi.org/10.1115/1.4068633
Published Online: May 9, 2025
View Articletitled, Deformation Response of the Human Lamina Cribrosa to Intracranial Pressure Lowering
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Topics: Deformation, Pressure, Drainage, Biological tissues, Cerebrospinal fluid, Coherence (Optics), Imaging, Shear (Mechanics)
Journal Articles

Biomechanical Strain Responses in the Sclera, Choroid, and Retina in Glaucoma Patients After Intraocular Pressure Lowering

Available to Purchase
Zhuochen Yuan, Cameron A. Czerpak, Michael Saheb Kashaf, Harry A. Quigley, Thao D. Nguyen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2025, 147(5): 051008.
Paper No: BIO-24-1245
https://doi.org/10.1115/1.4068155
Published Online: March 28, 2025
View Articletitled, Biomechanical Strain Responses in the Sclera, Choroid, and Retina in Glaucoma Patients After Intraocular Pressure Lowering
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Topics: Biological tissues, Pressure, Coherence (Optics), Biomechanics, Imaging
Includes: Supplementary data
Journal Articles

Eyelid Motion Tracking During Blinking Using High-Speed Imaging and Digital Image Correlation

Available to Purchase
Andrew Seamone, Jeremy N. Shapiro, Zhenyang Zhao, Vinay K. Aakalu, Anthony M. Waas, Christine Nelson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2025, 147(1): 014503.
Paper No: BIO-24-1078
https://doi.org/10.1115/1.4067082
Published Online: November 27, 2024
View Articletitled, Eyelid Motion Tracking During Blinking Using High-Speed Imaging and Digital Image Correlation
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Topics: Imaging, Kinematics, Displacement, Computer software
Journal Articles

In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior

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Huiming Dong, Henrik Haraldsson, Joseph Leach, Ang Zhou, Megan Ballweber, Chengcheng Zhu, Yue Xuan, Zhongjie Wang, Michael Hope, Frederick H. Epstein, Liang Ge, David Saloner, Elaine Tseng, Dimitrios Mitsouras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121009.
Paper No: BIO-23-1137
https://doi.org/10.1115/1.4066430
Published Online: October 3, 2024
View Articletitled, In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior
Open the PDF for In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior in another window
Topics: Aneurysms, Aorta, Displacement, Echoes, Encryption, Failure, Imaging, Magnetic resonance imaging, Maintenance, Mechanical testing
Includes: Supplementary data
Journal Articles

A Histomorphometric and Computational Investigation of the Stabilizing Role of Pectinate Ligaments in the Aqueous Outflow Pathway

Free
Babak N. Safa, Nina Sara Fraticelli Guzmán, Guorong Li, W. Daniel Stamer, Andrew J. Feola, C. Ross Ethier
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2024, 146(8): 081011.
Paper No: BIO-23-1388
https://doi.org/10.1115/1.4065164
Published Online: April 17, 2024
View Articletitled, A Histomorphometric and Computational Investigation of the Stabilizing Role of Pectinate Ligaments in the Aqueous Outflow Pathway
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Topics: Biological tissues, Biomechanics, Canals, Finite element analysis, Outflow, Stiffness, Collapse, Finite element model, Imaging
Includes: Supplementary data
Journal Articles

A Mechanics-Based Perspective on the Function of Human Sphincters During Functional Luminal Imaging Probe Manometry

Free
Guy Elisha, Sourav Halder, Dustin A. Carlson, Wenjun Kou, Peter J. Kahrilas, John E. Pandolfino, Neelesh A. Patankar
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2024, 146(2): 021001.
Paper No: BIO-23-1025
https://doi.org/10.1115/1.4064125
Published Online: December 12, 2023
View Articletitled, A Mechanics-Based Perspective on the Function of Human Sphincters During Functional Luminal Imaging Probe Manometry
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Topics: Pressure, Relaxation (Physics), Cycles, Fluids, Muscle, Imaging, Probes
Journal Articles

A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State

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Hao Liu, Natalie T. Simonian, Alison M. Pouch, Paul A. Iaizzo, Joseph H. Gorman, III, Robert C. Gorman, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111002.
Paper No: BIO-23-1060
https://doi.org/10.1115/1.4062849
Published Online: August 2, 2023
View Articletitled, A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State
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Topics: Geometry, Valves, Simulation, Pipelines, Maintenance, Calibration, Imaging
Journal Articles

The Curvature, Collagen Network Structure, and Their Relationship to the Pressure-Induced Strain Response of the Human Lamina Cribrosa in Normal and Glaucoma Eyes

Free
Cameron A. Czerpak, Yik Tung Tracy Ling, Joan L. Jefferys, Harry A. Quigley, Thao D. Nguyen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2023, 145(10): 101005.
Paper No: BIO-22-1074
https://doi.org/10.1115/1.4062846
Published Online: July 14, 2023
View Articletitled, The Curvature, Collagen Network Structure, and Their Relationship to the Pressure-Induced Strain Response of the Human Lamina Cribrosa in Normal and Glaucoma Eyes
Open the PDF for The Curvature, Collagen Network Structure, and Their Relationship to the Pressure-Induced Strain Response of the Human Lamina Cribrosa in Normal and Glaucoma Eyes in another window
Topics: Biological tissues, Damage, Density, Imaging, Pressure, Performance, Algorithms, Displacement, Anisotropy
Includes: Supplementary data
Journal Articles

The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers

Free
Thao (Vicky) Nguyen, C. Ross Ethier
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. August 2023, 145(8): 080202.
Paper No: BIO-23-1214
https://doi.org/10.1115/1.4062744
Published Online: June 28, 2023
View Articletitled, The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers
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Topics: Deformation, Fluids, Osteoarthritis, Bioengineering, Students, Algorithms, Arches, Armor, Bearings, Biological tissues
Journal Articles

The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I

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Mohamad Motaz F. Al Samman, Alaaddin Ibrahimy, Blaise Simplice Talla Nwotchouang, John N. Oshinski, Daniel L. Barrow, Philip A. Allen, Rouzbeh Amini, Rafeeque A. Bhadelia, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081005.
Paper No: BIO-23-1003
https://doi.org/10.1115/1.4062723
Published Online: June 21, 2023
View Articletitled, The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I
Open the PDF for The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I in another window
Topics: Biological tissues, Cardiac cycle, Damage, Displacement, Magnetic resonance imaging, Rotation, Spinal cord, Biomechanics, Encryption, Nervous system
Journal Articles

Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration

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Ellen T. Bloom, Lily M. Lin, Ryan C. Locke, Alyssa Giordani, Erin Krassan, John M. Peloquin, Karin Grävare Silbernagel, Justin Parreno, Michael H. Santare, Megan L. Killian, Dawn M. Elliott
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081003.
Paper No: BIO-22-1305
https://doi.org/10.1115/1.4062523
Published Online: June 16, 2023
View Articletitled, Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration
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Topics: Biological tissues, Imaging, Stress, Tendons, Scanning electron microscopy, Surgery, Magnetic resonance imaging, Ablation (Vaporization technology), Microscale devices, Cycles
Includes: Supplementary data
Journal Articles

Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach

Free
Mary Chase Sheehan, Scott Collins, Thomas Wimmer, Narendra Babu Gutta, Sebastian Monette, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2023, 145(9): 091004.
Paper No: BIO-22-1236
https://doi.org/10.1115/1.4062491
Published Online: May 22, 2023
View Articletitled, Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach
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Topics: Ablation (Vaporization technology), Biological tissues, Damage, Electrodes, Electroporation, Simulation, Tumors, Wire, Catheters, Electric fields
Includes: Supplementary data
Journal Articles

How Many Trials Are Needed to Estimate Typical Lumbar Movement Patterns During Dynamic X-Ray Imaging?

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Ameet Aiyangar, Tom Gale, Sabreen Magherhi, William Anderst
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2023, 145(7): 074503.
Paper No: BIO-22-1268
https://doi.org/10.1115/1.4062117
Published Online: April 8, 2023
View Articletitled, How Many Trials Are Needed to Estimate Typical Lumbar Movement Patterns During Dynamic X-Ray Imaging?
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Topics: Imaging, Kinematics, Lumbar spine, Radiation (Physics), Uncertainty, X-ray imaging, Reliability, Biomechanics
Journal Articles

Conditions for Use and Implementation of Globally-Aligned Versus Local Baseplate Coordinate Systems When Computing Migration Using Radiostereometric Analysis

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Abigail E. Niesen, Bart L. Kaptein, Maury L. Hull
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2023, 145(6): 061010.
Paper No: BIO-22-1250
https://doi.org/10.1115/1.4056802
Published Online: March 8, 2023
View Articletitled, Conditions for Use and Implementation of Globally-Aligned Versus Local Baseplate Coordinate Systems When Computing Migration Using Radiostereometric Analysis
Open the PDF for Conditions for Use and Implementation of Globally-Aligned Versus Local Baseplate Coordinate Systems When Computing Migration Using Radiostereometric Analysis in another window
Topics: Degrees of freedom, Displacement, Imaging, Rotation, Stability, Surgery, Calibration, Subsidence
Journal Articles

Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles

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Ning-Jiun Jan, Po-Yi Lee, Jacob Wallace, Michael Iasella, Alexandra Gogola, Bingrui Wang, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. May 2023, 145(5): 054503.
Paper No: BIO-22-1243
https://doi.org/10.1115/1.4056354
Published Online: December 21, 2022
View Articletitled, Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles
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Topics: Biological tissues, Clamps (Tools), Failure, Fibers, Biomechanics, Imaging, Polarization (Light)
Journal Articles

Stiffness and Strain Properties Derived From Digital Tomosynthesis-Based Digital Volume Correlation Predict Vertebral Strength Independently From Bone Mineral Density

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Yener N. Yeni, Daniel Oravec, Joshua Drost, Roger Zauel, Michael J. Flynn
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041009.
Paper No: BIO-22-1166
https://doi.org/10.1115/1.4056196
Published Online: December 5, 2022
View Articletitled, Stiffness and Strain Properties Derived From Digital Tomosynthesis-Based Digital Volume Correlation Predict Vertebral Strength Independently From Bone Mineral Density
Open the PDF for Stiffness and Strain Properties Derived From Digital Tomosynthesis-Based Digital Volume Correlation Predict Vertebral Strength Independently From Bone Mineral Density in another window
Topics: Bone, Density, Displacement, Imaging, Minerals, Regression models, Stiffness, Stress, Fracture (Materials), Fracture (Process)
Journal Articles

Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy

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Scott C. Sibole, Eng Kuan Moo, Salvatore Federico, Walter Herzog
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021005.
Paper No: BIO-22-1117
https://doi.org/10.1115/1.4055308
Published Online: October 6, 2022
View Articletitled, Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy
Open the PDF for Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy in another window
Topics: Biological tissues, Cartilage, Chondrocytes, Deformation, Image registration, Image segmentation, Resonance, Osmosis, Computer software, Imaging
Journal Articles

A Noninvasive Assessment of Flow Based on Contrast Dispersion in Computed Tomography Angiography: A Computational and Experimental Phantom Study

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Parastou Eslami, Jung-Hee Seo, Amir Ali Rahsepar, Asim Shafique, Shirley F. Rollison, Albert C. Lardo, Rajat Mittal, Marcus Y. Chen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091009.
Paper No: BIO-20-1358
https://doi.org/10.1115/1.4053997
Published Online: April 1, 2022
View Articletitled, A Noninvasive Assessment of Flow Based on Contrast Dispersion in Computed Tomography Angiography: A Computational and Experimental Phantom Study
Open the PDF for A Noninvasive Assessment of Flow Based on Contrast Dispersion in Computed Tomography Angiography: A Computational and Experimental Phantom Study in another window
Topics: Flow (Dynamics), Phantoms, Imaging, Computerized tomography
Includes: Supplementary data
Journal Articles

A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network

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Po-Yi Lee, Yi Hua, Bryn L. Brazile, Bin Yang, Lin Wang, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061006.
Paper No: BIO-21-1403
https://doi.org/10.1115/1.4054056
Published Online: March 24, 2022
View Articletitled, A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network
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Topics: Vessels, Workflow, Imaging, Biological tissues
Journal Articles

Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion

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Ru Wang, Jheng-Han Tsai, Martin P. Snead, Philip Alexander, D. Ian Wilson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2022, 144(5): 051004.
Paper No: BIO-20-1459
https://doi.org/10.1115/1.4053004
Published Online: December 20, 2021
View Articletitled, Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion
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Topics: Computational fluid dynamics, Flow (Dynamics), Fluids, Silicones, Simulation, Stability, Surface tension, Surfactants, Viscosity, Shapes
Includes: Supplementary data