Volume 131 Issue 7 | J. Biomech Eng. | ASME Digital Collection

Guest Editorial

Biotransport Special Issue

Alptekin Aksan, Ph.D., Allison Hubel, Ph.D., John Bischof, Ph.D.

J Biomech Eng. July 2009, 131(7): 070301. doi: https://doi.org/10.1115/1.3185352

View articletitled, Biotransport Special Issue

Topics: Biotransport , Cancer , Patient treatment , Proteins , Biomembranes , Molecular biophysics , Nanotechnology , Tumors

Research Papers

Thermally-Induced Change in the Relaxation Behavior of Skin Tissue

F. Xu, T. J. Lu, K. A. Seffen

J Biomech Eng. July 2009, 131(7): 071001. doi: https://doi.org/10.1115/1.3118766

Abstract

View articletitled, Thermally-Induced Change in the Relaxation Behavior of Skin Tissue

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Topics: Biological tissues , Relaxation (Physics) , Skin , Stress , Temperature

Insights Into Crowding Effects on Protein Stability From a Coarse-Grained Model

Vincent K. Shen, Jason K. Cheung, Jeffrey R. Errington, Thomas M. Truskett

J Biomech Eng. July 2009, 131(7): 071002. doi: https://doi.org/10.1115/1.3127259

Abstract

View articletitled, Insights Into Crowding Effects on Protein Stability From a Coarse-Grained Model

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Topics: Proteins , Stability , Simulation

Dynamic Effect of Heat Shock Pretreatment on Apoptotic Responses to $TNF- α$ in Liver Cells

Sihong Wang, Pohun C. Chen, Francois Berthiaume, Mehmet Toner, Arul Jayaraman, Martin L. Yarmush

J Biomech Eng. July 2009, 131(7): 071003. doi: https://doi.org/10.1115/1.3118768

Abstract

View articletitled, Dynamic Effect of Heat Shock Pretreatment on Apoptotic Responses to <math xmlns="http://www.w3.org/1998/Math/MathML"><mrow xmlns=""><mtext>TNF-</mtext><mi>α</mi></mrow></math> in Liver Cells

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Topics: Heat , Proteins , Shock (Mechanics) , Tumors , Liver , Stress

Evaluation of Effectiveness of Er,Cr:YSGG Laser For Root Canal Disinfection: Theoretical Simulation of Temperature Elevations in Root Dentin

L. Zhu, M. Tolba, D. Arola, M. Salloum, F. Meza

J Biomech Eng. July 2009, 131(7): 071004. doi: https://doi.org/10.1115/1.3147801

Abstract

View articletitled, Evaluation of Effectiveness of Er,Cr:YSGG Laser For Root Canal Disinfection: Theoretical Simulation of Temperature Elevations in Root Dentin

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Topics: Biological tissues , Canals , Lasers , Temperature , Heating , Simulation , Temperature distribution , Heat

Heat Loss Through the Glabrous Skin Surfaces of Heavily Insulated, Heat-Stressed Individuals

D. A. Grahn, Ph.D., J. L. Dillon, H. C. Heller, Ph.D.

J Biomech Eng. July 2009, 131(7): 071005. doi: https://doi.org/10.1115/1.3156812

Abstract

View articletitled, Heat Loss Through the Glabrous Skin Surfaces of Heavily Insulated, Heat-Stressed Individuals

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Topics: Heat , Heat losses , Pressure , Skin , Stress , Temperature , Cooling , Water , Insulation , Heat transfer

Electrical Field and Temperature Model of Nonthermal Irreversible Electroporation in Heterogeneous Tissues

Charlotte Daniels, Boris Rubinsky

J Biomech Eng. July 2009, 131(7): 071006. doi: https://doi.org/10.1115/1.3156808

Abstract

View articletitled, Electrical Field and Temperature Model of Nonthermal Irreversible Electroporation in Heterogeneous Tissues

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Topics: Biological tissues , Electric fields , Electroporation , Temperature , Blood vessels , Tumors , Surgery , Electrodes , Ducts , Temperature distribution

Voxelized Model of Interstitial Transport in the Rat Spinal Cord Following Direct Infusion Into White Matter

Jung Hwan Kim, Garrett W. Astary, Xiaoming Chen, Thomas H. Mareci, Malisa Sarntinoranont

J Biomech Eng. July 2009, 131(7): 071007. doi: https://doi.org/10.1115/1.3169248

Abstract

View articletitled, Voxelized Model of Interstitial Transport in the Rat Spinal Cord Following Direct Infusion Into White Matter

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Topics: Biological tissues , Imaging , Spinal cord , Tensors , Diffusion (Physics) , Resolution (Optics) , Image segmentation

Technology Reviews

Nanoparticles for Thermal Cancer Therapy

Emily S. Day, Jennifer G. Morton, Jennifer L. West

J Biomech Eng. July 2009, 131(7): 074001. doi: https://doi.org/10.1115/1.3156800

Abstract

View articletitled, Nanoparticles for Thermal Cancer Therapy

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Topics: Cancer , Heating , Nanoparticles , Patient treatment , Tumors , Radiofrequency ablation , Biological tissues , Temperature

Oxygen Transport in Brain Tissue

Kazuto Masamoto, Kazuo Tanishita

J Biomech Eng. July 2009, 131(7): 074002. doi: https://doi.org/10.1115/1.3184694

Abstract

View articletitled, Oxygen Transport in Brain Tissue

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Topics: Biological tissues , Blood flow , Brain , Oxygen

Adjuvant Approaches to Enhance Cryosurgery

Raghav Goel, Kyle Anderson, Joel Slaton, Franz Schmidlin, Greg Vercellotti, John Belcher, John C. Bischof

J Biomech Eng. July 2009, 131(7): 074003. doi: https://doi.org/10.1115/1.3156804

Abstract

View articletitled, Adjuvant Approaches to Enhance Cryosurgery

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Topics: Biological tissues , Cancer , Freezing , Temperature , Wounds , Diseases , Probes , Patient treatment , Surgery , Ice

Frontiers in Biotransport: Water Transport and Hydration

Alptekin Aksan, Allison Hubel, John C. Bischof

J Biomech Eng. July 2009, 131(7): 074004. doi: https://doi.org/10.1115/1.3173281

Abstract

View articletitled, Frontiers in Biotransport: Water Transport and Hydration

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Topics: Biological tissues , Water , Biotransport

Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics

Todd O. Pangburn, Matthew A. Petersen, Brett Waybrant, Maroof M. Adil, Efrosini Kokkoli

J Biomech Eng. July 2009, 131(7): 074005. doi: https://doi.org/10.1115/1.3160763

Abstract

View articletitled, Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics

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Topics: Cancer , DNA , Drug delivery systems , Drugs , Nanoparticles , Proteins , Tumors , Vehicles , Patient treatment

Technical Briefs

Model for Heat and Mass Transfer in Freeze-Drying of Pellets

Ioan Cristian Trelea, Stéphanie Passot, Michèle Marin, Fernanda Fonseca

J Biomech Eng. July 2009, 131(7): 074501. doi: https://doi.org/10.1115/1.3142975

Abstract

View articletitled, Model for Heat and Mass Transfer in Freeze-Drying of Pellets

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Topics: Drying , Heat , Mass transfer , Slabs , Temperature

Characterizing Ice Crystal Growth Behavior Under Electric Field Using Phase Field Method

Zhi Zhu He, Jing Liu

J Biomech Eng. July 2009, 131(7): 074502. doi: https://doi.org/10.1115/1.3142978

Abstract

View articletitled, Characterizing Ice Crystal Growth Behavior Under Electric Field Using Phase Field Method

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Topics: Crystal growth , Electric fields , Ice , Noise (Sound) , Microscale devices

Strain-Dependent Oxygen Diffusivity in Bovine Annulus Fibrosus

T.-Y. Yuan, A. R. Jackson, C.-Y. Huang, W. Y. Gu

J Biomech Eng. July 2009, 131(7): 074503. doi: https://doi.org/10.1115/1.3127254

Abstract

View articletitled, Strain-Dependent Oxygen Diffusivity in Bovine Annulus Fibrosus

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Topics: Compression , Oxygen , Annulus , Biological tissues , Diffusion (Physics) , Intervertebral discs

The Deformation Behavior of Multiple Red Blood Cells in a Capillary Vessel

Xiaobo Gong, Kazuyasu Sugiyama, Shu Takagi, Yoichiro Matsumoto

J Biomech Eng. July 2009, 131(7): 074504. doi: https://doi.org/10.1115/1.3127255

Abstract

View articletitled, The Deformation Behavior of Multiple Red Blood Cells in a Capillary Vessel

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Topics: Deformation , Erythrocytes , Vessels , Flow (Dynamics) , Viscosity , Membranes , Blood flow

A Microfluidic Manipulator for Enrichment and Alignment of Moving Cells and Particles

Hsiu-hung Chen, Bingbing Sun, Kenny K. Tran, Hong Shen, Dayong Gao

J Biomech Eng. July 2009, 131(7): 074505. doi: https://doi.org/10.1115/1.3127258

Abstract

View articletitled, A Microfluidic Manipulator for Enrichment and Alignment of Moving Cells and Particles

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Topics: Microfluidics , Particulate matter , Flow (Dynamics)

A Generic Bioheat Transfer Thermal Model for a Perfused Tissue

Devashish Shrivastava, J. Thomas Vaughan

J Biomech Eng. July 2009, 131(7): 074506. doi: https://doi.org/10.1115/1.3127260

Abstract

View articletitled, A Generic Bioheat Transfer Thermal Model for a Perfused Tissue

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Topics: Biological tissues , Blood , Temperature , Vessels , Heat transfer , Bioheat transfer , Blood vessels

Thermal Therapy in Urologic Systems: A Comparison of Arrhenius and Thermal Isoeffective Dose Models in Predicting Hyperthermic Injury

Xiaoming He, Sankha Bhowmick, John C. Bischof

J Biomech Eng. July 2009, 131(7): 074507. doi: https://doi.org/10.1115/1.3128671

Abstract

View articletitled, Thermal Therapy in Urologic Systems: A Comparison of Arrhenius and Thermal Isoeffective Dose Models in Predicting Hyperthermic Injury

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Topics: Biological tissues , Kidney , Temperature , Wounds , Patient treatment

Effect of Formalin Fixation on Thermal Conductivity of the Biological Tissue

Nachiket M. Kharalkar, Steven C. Bauserman, Jonathan W. Valvano

J Biomech Eng. July 2009, 131(7): 074508. doi: https://doi.org/10.1115/1.3147745

Abstract

View articletitled, Effect of Formalin Fixation on Thermal Conductivity of the Biological Tissue

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Topics: Biological tissues , Thermal conductivity , Liver

A Preliminary Study to Delineate Irreversible Electroporation From Thermal Damage Using the Arrhenius Equation

Hadi Shafiee, Paulo A. Garcia, Rafael V. Davalos

J Biomech Eng. July 2009, 131(7): 074509. doi: https://doi.org/10.1115/1.3143027

Abstract

View articletitled, A Preliminary Study to Delineate Irreversible Electroporation From Thermal Damage Using the Arrhenius Equation

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Topics: Biological tissues , Damage , Electroporation , Electric fields , Heating , Joules

Modeling Heat Shock Protein Expression Produced by a Heat Wrap

Alfred S. Song, Kenneth R. Diller

J Biomech Eng. July 2009, 131(7): 074510. doi: https://doi.org/10.1115/1.3143030

Abstract

View articletitled, Modeling Heat Shock Protein Expression Produced by a Heat Wrap

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Topics: Biological tissues , Heat , Proteins , Shock (Mechanics) , Temperature , Muscle , Heating

Effect of Controlled Ice Nucleation on Primary Drying Stage and Protein Recovery in Vials Cooled in a Modified Freeze-Dryer

Stéphanie Passot, Ioan Cristian Tréléa, Michèle Marin, Miquel Galan, G. John Morris, Fernanda Fonseca

J Biomech Eng. July 2009, 131(7): 074511. doi: https://doi.org/10.1115/1.3143034

Abstract

View articletitled, Effect of Controlled Ice Nucleation on Primary Drying Stage and Protein Recovery in Vials Cooled in a Modified Freeze-Dryer

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Topics: Drying , Freezing , Ice , Nucleation (Physics) , Proteins , Temperature , Freeze drying equipment , Ultrasound

Numerical Simulation of Au Nanoparticles Effect on the PCR Process

Chao Chen, Aili Zhang, Xiaodong Zhang, Jun Hu, Lisa X. Xu

J Biomech Eng. July 2009, 131(7): 074512. doi: https://doi.org/10.1115/1.3147746

Abstract

View articletitled, Numerical Simulation of Au Nanoparticles Effect on the PCR Process

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Topics: Nanoparticles , DNA

Freezing-Assisted Intracellular Drug Delivery to Multidrug Resistant Cancer Cells

Ka Yaw Teo, Bumsoo Han

J Biomech Eng. July 2009, 131(7): 074513. doi: https://doi.org/10.1115/1.3153325

Abstract

View articletitled, Freezing-Assisted Intracellular Drug Delivery to Multidrug Resistant Cancer Cells

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Topics: Cancer , Drug delivery systems , Drugs , Freezing , Proteins , Fluorescence , Membranes , Cell membranes , Microscopy

Biocompatible Ionic Liquids: A New Approach for Stabilizing Proteins in Liquid Formulation

Regina M. Vrikkis, Kevin J. Fraser, Kyoko Fujita, Douglas R. MacFarlane, Gloria D. Elliott

J Biomech Eng. July 2009, 131(7): 074514. doi: https://doi.org/10.1115/1.3156810

Abstract

View articletitled, Biocompatible Ionic Liquids: A New Approach for Stabilizing Proteins in Liquid Formulation

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Topics: Biocompatibility , Proteins , Polishing equipment , Enthalpy , Drugs

Encapsulation of Living Cells in Small $(\sim 100 μ m)$ Alginate Microcapsules by Electrostatic Spraying: A Parametric Study

Wujie Zhang, Xiaoming He

J Biomech Eng. July 2009, 131(7): 074515. doi: https://doi.org/10.1115/1.3153326

Abstract

View articletitled, Encapsulation of Living Cells in Small <math xmlns="http://www.w3.org/1998/Math/MathML"><mrow xmlns=""><mrow><mo>(</mo><mrow><mo>∼</mo><mn>100</mn><mtext> </mtext><mi>μ</mi><mtext>m</mtext></mrow><mo>)</mo></mrow></mrow></math> Alginate Microcapsules by Electrostatic Spraying: A Parametric Study

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Topics: Biological cells , Flow (Dynamics) , Microencapsulation , Sodium , Sprays , Density , Plasma spraying , Spraying (Coating processes)

Bubble Motion in a Blood Vessel: Shear Stress Induced Endothelial Cell Injury

K. Mukundakrishnan, P. S. Ayyaswamy, D. M. Eckmann

J Biomech Eng. July 2009, 131(7): 074516. doi: https://doi.org/10.1115/1.3153310

Abstract

View articletitled, Bubble Motion in a Blood Vessel: Shear Stress Induced Endothelial Cell Injury

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Topics: Blood vessels , Bubbles , Endothelial cells , Flow (Dynamics) , Shear stress , Wounds , Vessels , Vortices , Shear (Mechanics)

Effect of ${Me}_{2} SO$ on Membrane Phase Behavior and Protein Denaturation of Human Pulmonary Endothelial Cells Studied by In Situ FTIR Spectroscopy

Ralf Spindler, Willem F. Wolkers, Birgit Glasmacher

J Biomech Eng. July 2009, 131(7): 074517. doi: https://doi.org/10.1115/1.3156802

Abstract

View articletitled, Effect of <math xmlns="http://www.w3.org/1998/Math/MathML"><mrow xmlns=""><msub><mrow><mtext>Me</mtext></mrow><mn>2</mn></msub><mtext>SO</mtext></mrow></math> on Membrane Phase Behavior and Protein Denaturation of Human Pulmonary Endothelial Cells Studied by In Situ FTIR Spectroscopy

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Topics: Fourier transform infrared spectroscopy , Membranes , Proteins , Stability , Temperature , Endothelial cells , Heating

The Question of Thermal Waves in Heterogeneous and Biological Materials

Elaine P. Scott, Muluken Tilahun, Brian Vick

J Biomech Eng. July 2009, 131(7): 074518. doi: https://doi.org/10.1115/1.3167804

Abstract

View articletitled, The Question of Thermal Waves in Heterogeneous and Biological Materials

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Topics: Relaxation (Physics) , Temperature , Waves , Sensors , Uncertainty

Photoacoustic Detection of Melanoma Micrometastasis in Sentinel Lymph Nodes

Devin McCormack, Mays Al-Shaer, Benjamin S. Goldschmidt, Paul S. Dale, Carolyn Henry, Chris Papageorgio, Kiran Bhattacharyya, John A. Viator

J Biomech Eng. July 2009, 131(7): 074519. doi: https://doi.org/10.1115/1.3169247

Abstract

View articletitled, Photoacoustic Detection of Melanoma Micrometastasis in Sentinel Lymph Nodes

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Topics: Acoustics , Biological tissues , Cancer , Lasers , Sensors , Signals , Skin , Transducers , Waves

Structural Changes in Confined Lysozyme

Eduardo Reátegui, Alptekin Aksan

J Biomech Eng. July 2009, 131(7): 074520. doi: https://doi.org/10.1115/1.3171565

Abstract

View articletitled, Structural Changes in Confined Lysozyme

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Topics: Enzymes , Fluorescence , Fourier transform infrared spectroscopy , High temperature , Proteins , Temperature , Water , Dynamics (Mechanics) , Low temperature , Macromolecules