The reaction of articular cartilage and other soft tissues to mechanical loads has been characterized by coupled hydraulic (H) and mechanical (M) processes. An enhanced biphasic material model is presented, which may be used to describe the load response of soft tissue. A large-strain numerical approach of HM coupled processes has been applied. Physical and geometrical nonlinearities, as well as anisotropy and intrinsic rate-dependency of the solid skeleton have been realized using a thermodynamically consistent approach. The presented material model has been implemented into the commercially available finite element code MSC MARC. Initial verification of the model has been conducted analytically in tendonlike structures. The poroelastic and intrinsic viscoelastic features of the model were compared with the experimental data of an unconfined compression test of agarose hydrogel. A recent example from the area of cartilage research has been modeled, and the mechanical response was compared with cell viability. All examples showed good agreement between numerical and analytical/experimental results.
Skip Nav Destination
e-mail: Markus_A_Wimmer@rush.edu
Article navigation
July 2010
Technical Briefs
A Large Strain Material Model for Soft Tissues With Functionally Graded Properties
Uwe-Jens Görke,
Uwe-Jens Görke
Department of Environmental Informatics,
Helmholtz Centre for Environmental Research-UFZ
, Permoserstrasse 15, D-04318 Leipzig, Germany
Search for other works by this author on:
Hubert Günther,
Hubert Günther
AO Research Institute
, Clavadelerstrasse, CH-7270 Davos, Switzerland
Search for other works by this author on:
Thomas Nagel,
Thomas Nagel
Trinity Centre for Bioengineering, Mechanical and Manufacturing Engineering, School of Engineering,
Trinity College
, Dublin 2, Ireland
Search for other works by this author on:
Markus A. Wimmer
Markus A. Wimmer
Department of Orthopedic Surgery,
e-mail: Markus_A_Wimmer@rush.edu
Rush University Medical Center
, Amour Academic Facilities, Suite 761 1653 West Congress Parkway, Chicago, IL 60612
Search for other works by this author on:
Uwe-Jens Görke
Department of Environmental Informatics,
Helmholtz Centre for Environmental Research-UFZ
, Permoserstrasse 15, D-04318 Leipzig, Germany
Hubert Günther
AO Research Institute
, Clavadelerstrasse, CH-7270 Davos, Switzerland
Thomas Nagel
Trinity Centre for Bioengineering, Mechanical and Manufacturing Engineering, School of Engineering,
Trinity College
, Dublin 2, Ireland
Markus A. Wimmer
Department of Orthopedic Surgery,
Rush University Medical Center
, Amour Academic Facilities, Suite 761 1653 West Congress Parkway, Chicago, IL 60612e-mail: Markus_A_Wimmer@rush.edu
J Biomech Eng. Jul 2010, 132(7): 074502 (6 pages)
Published Online: June 2, 2010
Article history
Received:
September 14, 2009
Revised:
January 26, 2010
Posted:
February 22, 2010
Published:
June 2, 2010
Online:
June 2, 2010
Citation
Görke, U., Günther, H., Nagel, T., and Wimmer, M. A. (June 2, 2010). "A Large Strain Material Model for Soft Tissues With Functionally Graded Properties." ASME. J Biomech Eng. July 2010; 132(7): 074502. https://doi.org/10.1115/1.4001312
Download citation file:
Get Email Alerts
Simulating the Growth of TATA-Box Binding Protein-Associated Factor 15 Inclusions in Neuron Soma
J Biomech Eng (December 2024)
Related Articles
Simple Shear Testing of Parallel-Fibered Planar Soft Tissues
J Biomech Eng (April,2001)
The Micromechanical Environment of Intervertebral Disc Cells Determined by a Finite Deformation, Anisotropic, and Biphasic Finite Element Model
J Biomech Eng (February,2003)
A Finite Element Model of Cell-Matrix Interactions to Study the Differential Effect of Scaffold Composition on Chondrogenic Response to Mechanical Stimulation
J Biomech Eng (April,2011)
Poro-Viscoelastic Behavior of Gelatin Hydrogels Under Compression-Implications for Bioelasticity Imaging
J Biomech Eng (August,2009)
Related Proceedings Papers
Related Chapters
Characterization of Tissue Viscoelasticity from Shear Wave Speed Dispersion
Biomedical Applications of Vibration and Acoustics in Imaging and Characterizations
Linear Viscoelasticity
Introduction to Plastics Engineering
Conclusion
Ultrasonic Methods for Measurement of Small Motion and Deformation of Biological Tissues for Assessment of Viscoelasticity