Much research has been directed at improving the effectiveness of the radiofrequency (RF) ablation of hepatocellular carcinomas. In that point of view, this study was performed to provide comprehensive information of the relation between RF waveforms and thermodynamic response of the tissue with the consideration of four different types of RF waveforms (half-sine, half-square, half-exponential, and damped-sine) to maximize the amount of tumor tissue removed while maintaining the advantages of RF ablation. For the aim of this study, finite element models incorporating results from previous numerical models were used and validated with ex vivo experiments. From analyses of the entire results, we concluded that this study may prove valuable as a first step in providing comprehensive information of the relation between various RF waveforms and thermodynamic responses within the tissue during the RF ablation process. This study may also contribute toward studies to determine an optimum RF waveform capable of maximizing the amount of tumor tissue removed while maintaining the advantages of RF ablation.
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June 2010
Research Papers
Effect of Input Waveform Pattern and Large Blood Vessel Existence on Destruction of Liver Tumor Using Radiofrequency Ablation: Finite Element Analysis
Dohyung Lim,
Dohyung Lim
Gerontechnology Center,
Korea Institute of Industrial Technology
, Cheonan, Chungnam 330-825, Korea
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Bumseok Namgung,
Bumseok Namgung
Division of Bioengineering, and Department of Surgery,
National University of Singapore
, Singapore 117574, Singapore; Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering, Yonsei University
, Wonju, Gangwon 220-710, Korea
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Dae Gon Woo,
Dae Gon Woo
Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering,
Yonsei University
, Wonju, Gangwon 220-710, Korea
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Jin Seung Choi,
Jin Seung Choi
Department of Biomedical Engineering,
Konkuk University
, Chungju, Chungbuk 380-701, Korea
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Han Sung Kim,
Han Sung Kim
Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering,
Yonsei University
, Wonju, Gangwon 220-710, Korea
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Gye Rae Tack
Gye Rae Tack
Department of Biomedical Engineering,
e-mail: dli349@gmail.com
Konkuk University
, Chungju, Chungbuk 380-701, Korea
Search for other works by this author on:
Dohyung Lim
Gerontechnology Center,
Korea Institute of Industrial Technology
, Cheonan, Chungnam 330-825, Korea
Bumseok Namgung
Division of Bioengineering, and Department of Surgery,
National University of Singapore
, Singapore 117574, Singapore; Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering, Yonsei University
, Wonju, Gangwon 220-710, Korea
Dae Gon Woo
Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering,
Yonsei University
, Wonju, Gangwon 220-710, Korea
Jin Seung Choi
Department of Biomedical Engineering,
Konkuk University
, Chungju, Chungbuk 380-701, Korea
Han Sung Kim
Department of Biomedical Engineering, and Research Institute for Medical Instruments and Rehabilitation Engineering,
Yonsei University
, Wonju, Gangwon 220-710, Korea
Gye Rae Tack
Department of Biomedical Engineering,
Konkuk University
, Chungju, Chungbuk 380-701, Koreae-mail: dli349@gmail.com
J Biomech Eng. Jun 2010, 132(6): 061003 (8 pages)
Published Online: April 21, 2010
Article history
Received:
October 6, 2009
Revised:
January 12, 2010
Posted:
January 18, 2010
Published:
April 21, 2010
Online:
April 21, 2010
Citation
Lim, D., Namgung, B., Woo, D. G., Choi, J. S., Kim, H. S., and Tack, G. R. (April 21, 2010). "Effect of Input Waveform Pattern and Large Blood Vessel Existence on Destruction of Liver Tumor Using Radiofrequency Ablation: Finite Element Analysis." ASME. J Biomech Eng. June 2010; 132(6): 061003. https://doi.org/10.1115/1.4001029
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