Phospholipids and membrane proteins are two of the fundamental building blocks of cell membranes in living organisms. These molecules are amphipathic and synthetic membranes made of phospholipids, called bilayer lipid membranes (BLMs), are used to understand the characteristics of a cell membrane. Studies of these BLMs have been performed on both solid support and liquid support systems. A droplet interface bilayer (DIB) is a liquid support system where a monolayer is formed around a water droplet placed in oil and a bilayer is formed when two of these droplets are placed in contact. For impedance measurements, electrodes are placed in the water on each side of the bilayer. The measurements first insure there is a bilayer and second to obtain information about the bilayer. In a DIB system the electrodes pierce the monolayer surrounding the droplet causing instabilities in the monolayer. This study focuses on a non-invasive technique for measuring the bilayer by using the electrodes to contact the monolayer around the droplets and take impedance measurements without piercing the monolayer.
- Aerospace Division
Non-Invasive Measurement Techniques for Measuring Bilayers in Droplet-Interface-Bilayers
- Views Icon Views
- Share Icon Share
- Search Site
Creasy, MA, & Leo, DJ. "Non-Invasive Measurement Techniques for Measuring Bilayers in Droplet-Interface-Bilayers." Proceedings of the ASME 2009 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. Volume 2: Multifunctional Materials; Enabling Technologies and Integrated System Design; Structural Health Monitoring/NDE; Bio-Inspired Smart Materials and Structures. Oxnard, California, USA. September 21–23, 2009. pp. 639-645. ASME. https://doi.org/10.1115/SMASIS2009-1321
Download citation file: